Literature DB >> 32924787

Evaluation of Peroperative and Oncological Results in Laparoscopic Surgery of Gastric Cancer in Elderly Patients: Single-Center Study.

Afig Gojayev1, Ogün Erşen1, Ümit Mercan1, Cemil Yüksel1, Ömer Yalkın2, Sancar Bayar1, Ali Ekrem Ünal1, Salim Demirci1.   

Abstract

Introduction: Laparoscopic treatment of gastric cancer in elderly patients is still controversial. The aim of this retrospective study is to evaluate the safety and feasibility of laparoscopic gastrectomy in elderly gastric cancer patients based on the long- and short-term results of laparoscopic surgery. Materials and
Methods: The data of 163 patients who underwent laparoscopic gastrectomy for gastric cancer. Patients were categorized into two groups by age based on World Health Organization (WHO) criteria: elderly (≥65 years, 80 cases) and nonelderly (<65 years, 83 cases). Patient characteristics and clinicopathological findings, surgical findings, short- and long-term results were compared between the two groups.
Results: The patients in the study group were in the age range of 22-87 years and 80 (49%) patients were found out to be 65 years old or older. When all complications were categorized according to Clavien-Dindo (C-D) classification, >3 serious complication rates were similar between groups (P = .421). Although the length of hospital stay and the need for intensive care were higher in the elderly group, the difference was not significant (P = .066; P = .072). There was no significant difference between the two in terms of in-hospital mortality (P = .364). No statistically significant differences were found in the rates of overall survival (nonelderly group; 61.17 ± 3.34, 95% confidence interval [CI]: 54.61-67.74 versus elderly group; 56.48 ± 3.80, 95% CI: 49.03-63.93; P = .176) and disease-specific survival (nonelderly group; 64.24 ± 3.15, 95% CI: 58.06-70.40 versus elderly group; 61.93 ± 3.57, 95% CI: 54.93-68.93; P = .363) between the age groups.
Conclusion: In conclusion, although laparoscopic gastrectomy is a feasible and safe method in elderly gastric cancer patients, further randomized prospective studies are needed.

Entities:  

Keywords:  elderly patient; gastrectomy; gastric cancer; laparoscopy

Year:  2020        PMID: 32924787     DOI: 10.1089/lap.2020.0472

Source DB:  PubMed          Journal:  J Laparoendosc Adv Surg Tech A        ISSN: 1092-6429            Impact factor:   1.878


  1 in total

1.  miR-125a-5p promotes gastric cancer growth and invasion by regulating the Hippo pathway.

Authors:  Ruixin Li; Zhihao Hu; Zhuoyin Wang; Tianyu Zhu; Guojun Wang; Bulang Gao; Jingtao Wang; Xiumei Deng
Journal:  J Clin Lab Anal       Date:  2021-10-28       Impact factor: 2.352

  1 in total

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