Literature DB >> 3291981

The effect of stem cell proliferation regulators demonstrated with an in vitro assay.

I B Pragnell1, E G Wright, S A Lorimore, J Adam, M Rosendaal, J F DeLamarter, M Freshney, L Eckmann, A Sproul, N Wilkie.   

Abstract

Spleen colony formation after transplantation of bone marrow cells into irradiated mice has been used as an assay for hematopoietic stem cells (CFU-S), but has serious limitations intrinsic to an in vivo assay. In this report we describe experiments using an in vitro clonogenic assay that is especially suitable for studies of stem cell regulation as defined growth factors and normal untreated bone marrow can be used. We have demonstrated that the colony-forming cells have proliferative properties in common with CFU-S and respond to specific proliferation regulators previously detected using the spleen colony assay.

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Year:  1988        PMID： 3291981

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  11 in total

1.  Haematopoietic stem cell proliferation regulators investigated using an in vitro assay.

Authors:  S Robinson; A Riches
Journal:  J Anat       Date:  1991-02       Impact factor: 2.610

2.  The proliferative status of haematopoietic progenitor cells in the developing murine liver and adult bone marrow.

Authors:  A Blair; D B Thomas
Journal:  J Anat       Date:  1998-10       Impact factor: 2.610

3.  A novel in vitro assay for murine haematopoietic stem cells.

Authors:  L Eckmann; M Freshney; E G Wright; A Sproul; N Wilkie; I B Pragnell
Journal:  Br J Cancer Suppl       Date:  1988-12

4.  Beta-Chemokine CCL15 Affects the Adhesion and Migration of Hematopoietic Progenitor Cells.

Authors:  Rudolf Richter; Brigitte Rüster; Roxana Bistrian; Wolf-Georg Forssmann; Erhard Seifried; Reinhard Henschler
Journal:  Transfus Med Hemother       Date:  2014-12-19       Impact factor: 3.747

5.  Uncoupling of stem cell inhibition from monocyte chemoattraction in MIP-1alpha by mutagenesis of the proteoglycan binding site.

Authors:  G J Graham; P C Wilkinson; R J Nibbs; S Lowe; S O Kolset; A Parker; M G Freshney; M L Tsang; I B Pragnell
Journal:  EMBO J       Date:  1996-12-02       Impact factor: 11.598

6.  Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors.

Authors:  V P Patel; B L Kreider; Y Li; H Li; K Leung; T Salcedo; B Nardelli; V Pippalla; S Gentz; R Thotakura; D Parmelee; R Gentz; G Garotta
Journal:  J Exp Med       Date:  1997-04-07       Impact factor: 14.307

Review 7.  Molecular aspects of a negative regulator of haemopoiesis.

Authors:  M Plumb; G J Graham; M Grove; A Reid; I B Pragnell
Journal:  Br J Cancer       Date:  1991-12       Impact factor: 7.640

8.  Retrovirus mediated transfer and expression of GM-CSF in haematopoietic cells.

Authors:  W N Keith; R Brown; I B Pragnell
Journal:  Br J Cancer       Date:  1990-09       Impact factor: 7.640

9.  Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures.

Authors:  Jun Liu; Claire A Higgins; Jenna C Whitehouse; Susan J Harris; Heather Crawford; Angela M Christiano; Majlinda Lako; Nicholas Hole; Colin A B Jahoda
Journal:  Stem Cells Int       Date:  2018-08-02       Impact factor: 5.443

10.  Transforming growth factor beta: is it a downregulator of stem cell inhibition by macrophage inflammatory protein 1 alpha?

Authors:  J Maltman; I B Pragnell; G J Graham
Journal:  J Exp Med       Date:  1993-09-01       Impact factor: 14.307
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