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Literature DB >> 3291760

Anti-Candida albicans activity of Pichia anomala as determined by a growth rate reduction assay.

Abstract

Killer toxin activity of Pichia anomala WC65 appeared fungicidal for P. bimundalis WC38 and fungistatic for Candida albicans RC1. Inhibitory activity against sensitive C. albicans showed a linear relationship between toxin concentrations and the inverse of the reduced growth rates. The plot of toxin concentrations against growth rates was hyperbolic, as is characteristic of saturation kinetics. Sensitivity of C. albicans to the toxin decreased with increased cell age. The measurement of growth rate reduction provided a simple and accurate method for quantitation of toxin.

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Year: 1988 PMID： 3291760 PMCID： PMC202610 DOI： 10.1128/aem.54.5.1099-1103.1988

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

19 in total

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Journal: Antonie Van Leeuwenhoek Date: 1978 Impact factor: 2.271

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9 in total

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Authors: Ana Paula Paris; Cristiane Persel; Cleber Fernando Serafin; Rita de Cássia Garcia Simão; Rinaldo Ferreira Gandra
Journal: Curr Microbiol Date: 2016-09-16 Impact factor: 2.188

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Journal: Curr Genet Date: 1990-07 Impact factor: 3.886

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Authors: S Mischke
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