Literature DB >> 32916183

Considerations in developing medical countermeasures against chemical ocular toxicity.

David T Yeung1, Houmam Araj2, Jill R Harper3, Gennady E Platoff4.   

Abstract

The Chemical Countermeasures Research Program (CCRP) was established in 2006 by the National Institute of Allergy and Infectious Diseases (NIAID/NIH) on behalf of the National Institutes of Health Office of the Director (NIH OD). It is a trans-NIH initiative to expedite the discovery and early development of medical countermeasures (MCMs) that can reduce mortality and serious morbidity during and after large consequence public health emergency involving the deliberate or accidental large-scale release of highly toxic chemicals (HTCs). Published by Elsevier B.V.

Entities:  

Keywords:  CCRP; Chemical threats; Medical countermeasures; Ocular toxicity; Vesicants

Mesh:

Substances:

Year:  2020        PMID: 32916183      PMCID: PMC7606803          DOI: 10.1016/j.toxlet.2020.09.004

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN: 0378-4274            Impact factor:   4.372


  14 in total

1.  Medical mitigation model: quantifying the benefits of the public health response to a chemical terrorism attack.

Authors:  Kevin Good; David Winkel; Michael VonNiederhausern; Brian Hawkins; Jessica Cox; Rachel Gooding; Mark Whitmire
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2.  Office of the Assistant Secretary for Preparedness and Response; HHS Public Health Emergency Medical Countermeasures Enterprise implementation plan for chemical, biological, radiological and nuclear threats. Notice.

Authors: 
Journal:  Fed Regist       Date:  2007-04-23

Review 3.  Corneal toxicity induced by vesicating agents and effective treatment options.

Authors:  Dinesh G Goswami; Neera Tewari-Singh; Rajesh Agarwal
Journal:  Ann N Y Acad Sci       Date:  2016-06-21       Impact factor: 5.691

4.  National Institutes of Health (NIH) Executive Meeting Summary: Developing Medical Countermeasures to Rescue Opioid-Induced Respiratory Depression (a Trans-Agency Scientific Meeting)-August 6/7, 2019.

Authors:  David T Yeung; Kristopher J Bough; Jill R Harper; Gennady E Platoff
Journal:  J Med Toxicol       Date:  2019-12-18

5.  Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries.

Authors:  Neera Tewari-Singh; Anil K Jain; Swetha Inturi; David A Ammar; Chapla Agarwal; Puneet Tyagi; Uday B Kompella; Robert W Enzenauer; J Mark Petrash; Rajesh Agarwal
Journal:  Toxicol Appl Pharmacol       Date:  2012-07-24       Impact factor: 4.219

6.  Supporting Fundamental Chemical Toxicology Research To Inform Medical Countermeasure Developments: The National Institutes of Health Chemical Countermeasures Research Program.

Authors:  David T Yeung; Jill R Harper; Gennady E Platoff
Journal:  Chem Res Toxicol       Date:  2020-03-20       Impact factor: 3.739

7.  The National Institutes of Health Chemical Countermeasures Research Program (NIH CCRP): A collaborative opportunity to develop effective and accessible chemical medical countermeasures for the American people.

Authors:  David T Yeung; Jill R Harper; Gennady E Platoff
Journal:  Drug Dev Res       Date:  2020-06-22       Impact factor: 5.004

8.  ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure.

Authors:  Andrea DeSantis-Rodrigues; Yoke-Chen Chang; Rita A Hahn; Iris P Po; Peihong Zhou; C Jeffrey Lacey; Abhilash Pillai; Sherri C Young; Robert A Flowers; Michael A Gallo; Jeffrey D Laskin; Donald R Gerecke; Kathy K H Svoboda; Ned D Heindel; Marion K Gordon
Journal:  Invest Ophthalmol Vis Sci       Date:  2016-04       Impact factor: 4.799

9.  An Engineered Human Fibroblast Growth Factor-1 Derivative, TTHX1114, Ameliorates Short-term Corneal Nitrogen Mustard Injury in Rabbit Organ Cultures.

Authors:  David D Eveleth; Jennifer J Eveleth; Amuthakannan Subramaniam; Rita Hahn; Peihong Zhou; Marion K Gordon; Ralph A Bradshaw
Journal:  Invest Ophthalmol Vis Sci       Date:  2018-09-04       Impact factor: 4.799

10.  Architectural and biochemical expressions of mustard gas keratopathy: preclinical indicators and pathogenic mechanisms.

Authors:  Patrick McNutt; Megan Lyman; Adam Swartz; Kaylie Tuznik; Denise Kniffin; Kim Whitten; Denise Milhorn; Tracey Hamilton
Journal:  PLoS One       Date:  2012-08-10       Impact factor: 3.240

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  2 in total

1.  Supporting discovery and development of medical countermeasures for chemical injury to eye and skin.

Authors:  Houmam Araj; Hung Tseng; David T Yeung
Journal:  Exp Eye Res       Date:  2022-06-15       Impact factor: 3.770

Review 2.  The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas.

Authors:  Fu-Shin X Yu; Patrick S Y Lee; Lingling Yang; Nan Gao; Yangyang Zhang; Alexander V Ljubimov; Ellen Yang; Qingjun Zhou; Lixin Xie
Journal:  Prog Retin Eye Res       Date:  2022-01-04       Impact factor: 19.704

  2 in total

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