So Young Joo1, Yoon Soo Cho1, Kuem Ju Lee2, Seung Yeol Lee3, Cheong Hoon Seo1. 1. Department of Rehabilitation Medicine, Hangang Sacred Heart Hospital, College of Medicine, Hallym University, Seoul, Korea. 2. Department of Rehabilitation & Assistive Technology, Korea National Rehabilitation Research Institute, National Rehabilitation Center, Seoul, Korea. 3. Department of Physical Medicine and Rehabilitation, College of Medicine, Soonchunhyang University Hospital, Bucheon, Korea.
Abstract
BACKGROUND: Understanding the mechanisms associated with locomotor networks may be of benefit for rehabilitation of burn victims with neurological locomotor deficits. A wearable functional near-infrared spectroscopy (fNIRS) device has been developed for studying cortical hemodynamics. OBJECTIVES: To investigate cortical brain activity during usual walking, we examined patterns of cortical activation using fNIRS device (NIRSIT®; OBELAB Inc., Seoul, Korea), in patients with neurological injury caused by lower extremity burns. METHODS: This cross-sectional study assessed 15 patients with lower extremity burns, 10 patients with upper extremity burns, and 11 healthy controls. We measured walking-related cortical activity using an fNIRS device at baseline and during usual walking. RESULTS: There was no significant difference between the burns groups in terms of age (43.50 ± 14.08 and 44.67 ± 6.92 years, P = 1.00), pain score of NRS (Numeric rating scale) (5.83 ± 1.19 and 6.67 ± 1.21, P = 0.18) or the mean time since injury (228.50 ± 83.43 and 199.33 ± 68.84 days, P = 0.78). Measures showed increased cortical activation in the prefrontal cortex in patients with lower extremity burns than in patients with healthy controls(P = 0.015). The measured HbO2 datas of the regions during usual walking in patients with lower extremity burn were insignificantly higher compared with the datas in patient with upper extremity burn (P = 0.302). CONCLUSIONS: The patients with neurological injury due to lower extremity burns significantly rely more on cognitive resources even when performing a usual walking task.
BACKGROUND: Understanding the mechanisms associated with locomotor networks may be of benefit for rehabilitation of burn victims with neurological locomotor deficits. A wearable functional near-infrared spectroscopy (fNIRS) device has been developed for studying cortical hemodynamics. OBJECTIVES: To investigate cortical brain activity during usual walking, we examined patterns of cortical activation using fNIRS device (NIRSIT®; OBELAB Inc., Seoul, Korea), in patients with neurological injury caused by lower extremity burns. METHODS: This cross-sectional study assessed 15 patients with lower extremity burns, 10 patients with upper extremity burns, and 11 healthy controls. We measured walking-related cortical activity using an fNIRS device at baseline and during usual walking. RESULTS: There was no significant difference between the burns groups in terms of age (43.50 ± 14.08 and 44.67 ± 6.92 years, P = 1.00), pain score of NRS (Numeric rating scale) (5.83 ± 1.19 and 6.67 ± 1.21, P = 0.18) or the mean time since injury (228.50 ± 83.43 and 199.33 ± 68.84 days, P = 0.78). Measures showed increased cortical activation in the prefrontal cortex in patients with lower extremity burns than in patients with healthy controls(P = 0.015). The measured HbO2 datas of the regions during usual walking in patients with lower extremity burn were insignificantly higher compared with the datas in patient with upper extremity burn (P = 0.302). CONCLUSIONS: The patients with neurological injury due to lower extremity burns significantly rely more on cognitive resources even when performing a usual walking task.
Authors: Seung Yeol Lee; Jeong Yeon Cha; Ji Won Yoo; Matheu Nazareno; Yoon Soo Cho; So Young Joo; Cheong Hoon Seo Journal: J Clin Med Date: 2022-06-29 Impact factor: 4.964
Authors: Zhisong Zhang; Agnieszka Olszewska-Guizzo; Syeda Fabeha Husain; Jessica Bose; Jongkwan Choi; Wanqiu Tan; Jiayun Wang; Bach Xuan Tran; Bokun Wang; Yajie Jin; Wei Xuan; Pinjia Yan; Maomao Li; Cyrus S H Ho; Roger Ho Journal: Int J Environ Res Public Health Date: 2020-11-12 Impact factor: 3.390