| Literature DB >> 3291447 |
Abstract
The challenge to development of a malaria vaccine will be the variability of the sequences of target antigens. We discuss the variability in the T cell epitopes on the circumsporozoite protein of Plasmodium falciparum and the rapid selection of mutants after immunization with a protein from the asexual erythrocytic stage of P. knowlesi.Entities:
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Year: 1988 PMID： 3291447 DOI： 10.1016/s0264-410x(88)80008-2
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641