Nguyen Huu Dung1, Nguyen Duc Loc2, Dao Bui Quy Quyen3, Nguyen Minh Tuan4, Pham Ngoc Huy Tuan5, Do Quyet6, Le Viet Thang6,7. 1. Bach Mai Hospital, Hanoi, Vietnam. 2. An Sinh Hospital, Ho Chi Minh, Vietnam. 3. Cho Ray Hospital, Ho Chi Minh, Vietnam. 4. E Hospital, Ha Noi, Vietnam. 5. Trung Vuong Hospital, Ho Chi Minh, Vietnam. 6. Viet Nam Military Medical University, Hanoi, Vietnam. 7. Military Hospital 103, Hanoi, Vietnam.
Abstract
AIMS: Carpal tunnel syndrome (CTS) and low serum prealbumin concentration are common in maintenance hemodialysis patients. In this study, we focused on the association between low serum prealbumin levels and carpal tunnel syndrome in maintenance hemodialysis (MHD) patients using low-flux dialysis reuse. MATERIALS AND METHODS: Serum prealbumin levels were assessed to determine the association between low serum prealbumin levels and CTS in 373 prevalent MHD patients (the mean age was 45 years old, hemodialysis duration was 46 months). The patients were divided into 2 groups: the CTS group with 44 patients and the non-CTS group with 329 patients. RESULTS: The prevalence of CTS was 11.8%. Serum prealbumin showed a good prognostic value to predict CTS in MHD patients using low-flux dialysis reuse (the Area Under the Curve = 0.841, p < .001; cutoff value: 26.5 mg/dL with sensitivity = 72.7% and specificity = 79.9%). CONCLUSIONS: Serum prealbumin was a good prognostic biomarker of CTS in MHD patients using low-flux dialysis reuse.
AIMS: Carpal tunnel syndrome (CTS) and low serum prealbumin concentration are common in maintenance hemodialysis patients. In this study, we focused on the association between low serum prealbumin levels and carpal tunnel syndrome in maintenance hemodialysis (MHD) patients using low-flux dialysis reuse. MATERIALS AND METHODS: Serum prealbumin levels were assessed to determine the association between low serum prealbumin levels and CTS in 373 prevalent MHD patients (the mean age was 45 years old, hemodialysis duration was 46 months). The patients were divided into 2 groups: the CTS group with 44 patients and the non-CTS group with 329 patients. RESULTS: The prevalence of CTS was 11.8%. Serum prealbumin showed a good prognostic value to predict CTS in MHD patients using low-flux dialysis reuse (the Area Under the Curve = 0.841, p < .001; cutoff value: 26.5 mg/dL with sensitivity = 72.7% and specificity = 79.9%). CONCLUSIONS: Serum prealbumin was a good prognostic biomarker of CTS in MHD patients using low-flux dialysis reuse.
Authors: Mark J Sarnak; Roy Bloom; Paul Muntner; Mahboob Rahman; Jeffrey M Saland; Peter W F Wilson; Linda Fried Journal: Am J Kidney Dis Date: 2014-11-18 Impact factor: 8.860
Authors: Jerzy Kopeć; Artur Gadek; Maciej Drozdz; Krzysztof Miśkowiec; Julian Dutka; Antoni Sydor; Eve Chowaniec; Władysław Sułowicz Journal: Med Sci Monit Date: 2011-09