| Literature DB >> 32910386 |
A D Voronova1, O V Stepanova2,3, M P Valikhov2,3, A V Chadin2, A S Semkina2, E K Karsuntseva2,4, G A Fursa2,4, I V Reshetov5, V P Chekhonin2.
Abstract
In experiments on rats, co-transplantation of olfactory ensheathing cells of the human olfactory mucosa and neural stem/progenitor cells from the same source into post-traumatic cysts of the spinal cord led to improvement of the motor activity of the hind limbs and reduced the size of the cysts in some animals by 4-12%. The transplantation of a combination of the olfactory mucosa cells is effective and can be used in preclinical trials for the treatment of spinal cord injuries.Entities:
Keywords: cell therapy; human olfactory mucosa; neural stem/progenitor cells; olfactory ensheathing cells; post-traumatic cysts of spinal cord
Mesh：
Year: 2020 PMID： 32910386 DOI： 10.1007/s10517-020-04925-3
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804