Literature DB >> 32907424

Defensive antibacterial coating in revision total hip arthroplasty: new concept and early experience.

Massimo Franceschini1, N Amir Sandiford2, Vincenzo Cerbone1, Lucio Cappelli Toledo de Araujo3,4, Daniel Kendoff4.   

Abstract

BACKGROUND: Infections remains the most feared complication in total hip arthroplasty (THA). New strategies of PJI prevention includes coating of conventional implants. Defensive Antibacterial Coating (DAC), an antibacterial hydrogel coating made of hyaluronan, poly-D and L-lactide can protect biomaterials as an effective barrier at the time of implantation. In addition, it can be used with topical antibiotics to prevent early colonisation of the implant. SCOPE: This manuscript describes the detailed function of the DAC in general as well as an analysis of its use in revision THA in a series of 28 patients in a short-term follow-up.Its use in patients undergoing cementless re-implantation after 2-staged procedures in THA is described in detail within the manuscript.
CONCLUSION: DAC found to be effective in terms of infection control and safety in our patient cohort and has been expanded for cementless 1-staged revisions in PJI of the hip in our institution.

Entities:  

Keywords:  Antibacterial coating; PJI; cost; infection; revision arthroplasty; total hip arthroplasty

Mesh:

Substances:

Year:  2020        PMID: 32907424     DOI: 10.1177/1120700020917125

Source DB:  PubMed          Journal:  Hip Int        ISSN: 1120-7000            Impact factor:   2.135


  3 in total

Review 1.  Environmental, Microbiological, and Immunological Features of Bacterial Biofilms Associated with Implanted Medical Devices.

Authors:  Marina Caldara; Cristina Belgiovine; Eleonora Secchi; Roberto Rusconi
Journal:  Clin Microbiol Rev       Date:  2022-01-19       Impact factor: 50.129

Review 2.  Addressing the Needs of the Rapidly Aging Society through the Development of Multifunctional Bioactive Coatings for Orthopedic Applications.

Authors:  Tinkara Mastnak; Uroš Maver; Matjaž Finšgar
Journal:  Int J Mol Sci       Date:  2022-03-03       Impact factor: 5.923

3.  Trabecular Titanium for Orthopedic Applications: Balancing Antimicrobial with Osteoconductive Properties by Varying Silver Contents.

Authors:  Anna Diez-Escudero; Elin Carlsson; Brittmarie Andersson; Josef D Järhult; Nils P Hailer
Journal:  ACS Appl Mater Interfaces       Date:  2022-09-07       Impact factor: 10.383

  3 in total

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