Literature DB >> 32905332

Age-dependent increased odds of cardiovascular risk factors in cancer survivors: Canadian Longitudinal Study on Aging cohort.

A A Kirkham1, E Pituskin2, S E Neil-Sztramko3.   

Abstract

Background: This study compared the odds of self-reported and objectively measured cardiovascular (cv) risk factors in a sample of Canadian cancer survivors and individuals without cancer.
Methods: A nationally representative sample of 45- to 85-year-old cancer survivors (n = 6288) in the Canadian Longitudinal Study on Aging were compared with individuals without cancer (n = 44,051).
Results: The most prevalent risk factors in cancer survivors were all self-reported or easily measured in clinic: overweight or obesity (68.0%), former smoking (62.9%), fewer than 5 daily servings of fruits and vegetables (59.8%), hypertension (43.7%), and high waist circumference (47.0%). After adjustment for sex and education, the odds ratios of several cv risk factors varied by age in cancer survivors and the non-cancer controls. At ages 50 and 60, cancer survivors have increased odds of overweight or obesity, former smoking, hypertension, high waist circumference and truncal fat, diabetes, lung disease, and heart rate greater than 80 bpm compared with non-cancer controls. At age 70, odds did not differ for many risk factors; at age 80, no differences were evident. Without modification by age, low physical activity was more prevalent in cancer survivors (odds ratio: 1.27; 95% confidence interval: 1.17 to 1.39). There were no differences in the odds of cv risk factors measured by specialized equipment, including electrocardiography, carotid ultrasonography, spirometry, and dual-energy X-ray absorptiometry. Conclusions: The odds of several easy-to-assess cv disease risk factors are higher among middle-aged, but not older, cancer survivors relative to the general Canadian population. Initial assessment of cv risk for middle-aged adults in the survivorship setting could be quickly and inexpensively performed using self-reported and easily measured metrics. 2020 Multimed Inc.

Entities:  

Keywords:  Survivorship; cardiovascular risk factors; hypertension; obesity; physical activity; smoking

Mesh:

Year:  2020        PMID: 32905332      PMCID: PMC7467781          DOI: 10.3747/co.27.6117

Source DB:  PubMed          Journal:  Curr Oncol        ISSN: 1198-0052            Impact factor:   3.109


  20 in total

1.  Diabetes--a common, growing, serious, costly, and potentially preventable public health problem.

Authors:  K M Narayan; E W Gregg; A Fagot-Campagna; M M Engelgau; F Vinicor
Journal:  Diabetes Res Clin Pract       Date:  2000-10       Impact factor: 5.602

2.  Resting heart rate and all-cause and cardiovascular mortality in the general population: a meta-analysis.

Authors:  Dongfeng Zhang; Xiaoli Shen; Xin Qi
Journal:  CMAJ       Date:  2015-11-23       Impact factor: 8.262

3.  Nutrition screening index for older adults (SCREEN II) demonstrates sex and age invariance.

Authors:  Holly D Reimer; Heather H Keller; Scott B Maitland; Jessica Jackson
Journal:  J Nutr Elder       Date:  2010-04

4.  The self-reported Physical Activity Scale for the Elderly (PASE) is a valid and clinically applicable measure in lung cancer.

Authors:  Catherine L Granger; Selina M Parry; Linda Denehy
Journal:  Support Care Cancer       Date:  2015-03-26       Impact factor: 3.603

Review 5.  Carotid intima-media thickness measurements: what defines an abnormality? A systematic review.

Authors:  A Aminbakhsh; G B Mancini
Journal:  Clin Invest Med       Date:  1999-08       Impact factor: 0.825

Review 6.  Cardiotoxicity of chemotherapeutic agents: incidence, treatment and prevention.

Authors:  V B Pai; M C Nahata
Journal:  Drug Saf       Date:  2000-04       Impact factor: 5.606

7.  Death causes in breast cancer patients.

Authors:  M Riihimäki; H Thomsen; A Brandt; J Sundquist; K Hemminki
Journal:  Ann Oncol       Date:  2011-05-17       Impact factor: 32.976

8.  Cardiotoxicity in patients receiving transtuzumab (Herceptin): primary toxicity, synergistic or sequential stress, or surveillance artifact?

Authors:  M S Ewer; H R Gibbs; J Swafford; R S Benjamin
Journal:  Semin Oncol       Date:  1999-08       Impact factor: 4.929

9.  The Canadian longitudinal study on aging (CLSA).

Authors:  Parminder S Raina; Christina Wolfson; Susan A Kirkland; Lauren E Griffith; Mark Oremus; Christopher Patterson; Holly Tuokko; Margaret Penning; Cynthia M Balion; David Hogan; Andrew Wister; Hélène Payette; Harry Shannon; Kevin Brazil
Journal:  Can J Aging       Date:  2009-09

10.  An evidence-based comparison of operational criteria for the presence of sarcopenia.

Authors:  Thuy-Tien Dam; Katherine W Peters; Maren Fragala; Peggy M Cawthon; Tamara B Harris; Robert McLean; Michelle Shardell; Dawn E Alley; Anne Kenny; Luigi Ferrucci; Jack Guralnik; Douglas P Kiel; Steve Kritchevsky; Maria T Vassileva; Stephanie Studenski
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-05       Impact factor: 6.053

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  1 in total

Review 1.  Hypertension in Cancer Survivors.

Authors:  Mohammed Hasan Khan; Surabhi Pathak; Udit Yadav; Yogita Rochlani; Wilbert S Aronow
Journal:  Curr Hypertens Rep       Date:  2022-07-19       Impact factor: 4.592

  1 in total

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