Literature DB >> 3290091

Does lactobacillus vaccine for trichomoniasis, Solco Trichovac, induce antibody reactive with Trichomonas vaginalis?

J F Alderete1.   

Abstract

Solco Trichovac is a vaccine of Lactobacillus acidophilus developed for treating trichomoniasis. The efficacy of the vaccine is reportedly due to cross reacting antibody being produced in people immunised with the lactobacillus bacteria. Several techniques, including enzyme linked immunosorbent, indirect immunofluorescence, immunoblot, and radioimmunoprecipitation assays were used to assess the extent of antigenic cross reactivity between Lactobacillus acidophilus and Trichomonas vaginalis. Data show a lack of antigenic relatedness between the Solco Trichovac lactobacilli and several strains of T vaginalis. Furthermore, antiserum to L acidophilus failed to inhibit trichomonad cytadherence or host cell killing, as is suggested by the producers of the Solco Trichovac vaccine.

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Year:  1988        PMID: 3290091      PMCID: PMC1194170          DOI: 10.1136/sti.64.2.118

Source DB:  PubMed          Journal:  Genitourin Med        ISSN: 0266-4348


  15 in total

1.  Vaccination with SolcoTrichovac. Immunological aspects of a new approach for therapy and prophylaxis of trichomoniasis in women.

Authors:  R Pavic; L Stojković
Journal:  Gynakol Rundsch       Date:  1983

2.  New evidence elucidating the mechanism of action of Gynatren/SolcoTrichovac.

Authors:  L Stojković
Journal:  Gynakol Rundsch       Date:  1984

3.  Assay conditions and the demonstration of nitroimidazole resistance in Tritrichomonas foetus.

Authors:  J G Meingassner; H Mieth; R Czok; D G Lindmark; M Müller
Journal:  Antimicrob Agents Chemother       Date:  1978-01       Impact factor: 5.191

4.  Enzyme linked immunosorbent assay for detecting antibody to Trichomonas vaginalis: use of whole cells and aqueous extract as antigen.

Authors:  J F Alderete
Journal:  Br J Vener Dis       Date:  1984-06

5.  Monoclonal antibody to a major surface glycoprotein immunogen differentiates isolates and subpopulations of Trichomonas vaginalis.

Authors:  J F Alderete; L Suprun-Brown; L Kasmala
Journal:  Infect Immun       Date:  1986-04       Impact factor: 3.441

6.  Pathogenic Trichomonas vaginalis cytotoxicity to cell culture monolayers.

Authors:  J F Alderete; E Pearlman
Journal:  Br J Vener Dis       Date:  1984-04

7.  Antigen analysis of several pathogenic strains of Trichomonas vaginalis.

Authors:  J F Alderete
Journal:  Infect Immun       Date:  1983-03       Impact factor: 3.441

8.  Specific nature of Trichomonas vaginalis parasitism of host cell surfaces.

Authors:  J F Alderete; G E Garza
Journal:  Infect Immun       Date:  1985-12       Impact factor: 3.441

9.  Identification of immunogenic and antibody-binding membrane proteins of pathogenic Trichomonas vaginalis.

Authors:  J F Alderete
Journal:  Infect Immun       Date:  1983-04       Impact factor: 3.441

10.  Phenotypes and protein-epitope phenotypic variation among fresh isolates of Trichomonas vaginalis.

Authors:  J F Alderete; P Demĕs; A Gombosová; M Valent; A Yánoska; H Fabusová; L Kasmala; G E Garza; E C Metcalfe
Journal:  Infect Immun       Date:  1987-05       Impact factor: 3.441

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  5 in total

Review 1.  Clinical and microbiological aspects of Trichomonas vaginalis.

Authors:  D Petrin; K Delgaty; R Bhatt; G Garber
Journal:  Clin Microbiol Rev       Date:  1998-04       Impact factor: 26.132

Review 2.  Comparative aspects of immunity and vaccination in human and bovine trichomoniasis: a review.

Authors:  Aspinas Chapwanya; Abubakar Yusha'u Usman; Pete Charles Irons
Journal:  Trop Anim Health Prod       Date:  2015-09-30       Impact factor: 1.559

Review 3.  Treatment of infections caused by metronidazole-resistant Trichomonas vaginalis.

Authors:  Sarah L Cudmore; Kiera L Delgaty; Shannon F Hayward-McClelland; Dino P Petrin; Gary E Garber
Journal:  Clin Microbiol Rev       Date:  2004-10       Impact factor: 26.132

Review 4.  Vulvar pruritus-Causes, Diagnosis and Therapeutic Approach.

Authors:  Linn Woelber; Katharina Prieske; Werner Mendling; Barbara Schmalfeldt; Hans-Jürgen Tietz; Anna Jaeger
Journal:  Dtsch Arztebl Int       Date:  2020-02-21       Impact factor: 5.594

Review 5.  Trichomoniasis - are we giving the deserved attention to the most common non-viral sexually transmitted disease worldwide?

Authors:  Camila Braz Menezes; Amanda Piccoli Frasson; Tiana Tasca
Journal:  Microb Cell       Date:  2016-06-27
  5 in total

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