Literature DB >> 32900715

Emergency fasciotomy in an anticoagulated patient with low energy posterior thigh injury.

Verity Brooker1, Robert Brown2, Luke Thornton3, Edward Wood4.   

Abstract

We present a case of a 58-year-old patient with a low energy trauma developing compartment syndrome. He required multiple surgeries, including fasciotomy and removal of a large haematoma. He continued to bleed with a vacuum-assisted closure dressing in situ, requiring prothrombin complex Concentrate and blood transfusion. This case highlights the need for an increased awareness of possible development of compartment syndrome following low impact trauma in a patient who is anticoagulated and raises the question of a possible period of observation for those who may be at risk. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  orthopaedics; pharmacodynamics; trauma

Mesh:

Substances:

Year:  2020        PMID: 32900715      PMCID: PMC7478037          DOI: 10.1136/bcr-2019-232709

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

Review 1.  Diagnosing acute compartment syndrome.

Authors:  Kirsten G B Elliott; Alan J Johnstone
Journal:  J Bone Joint Surg Br       Date:  2003-07

2.  Compartment syndrome secondary to an atraumatic gastrocnemius tear in a patient on NOACs: presentation and complications of treatment.

Authors:  Georgina Stefanie Anne Phillips; Stephen Martin McDonnell
Journal:  BMJ Case Rep       Date:  2018-12-04

Review 3.  Direct Oral Anticoagulants: A Quick Guide.

Authors:  Sikorska Julia; Uprichard James
Journal:  Eur Cardiol       Date:  2017-08

4.  Management of rivaroxaban- or apixaban-associated major bleeding with prothrombin complex concentrates: a cohort study.

Authors:  Ammar Majeed; Anna Ågren; Margareta Holmström; Maria Bruzelius; Roza Chaireti; Jacob Odeberg; Eva-Lotta Hempel; Maria Magnusson; Tony Frisk; Sam Schulman
Journal:  Blood       Date:  2017-08-23       Impact factor: 22.113

Review 5.  New oral anticoagulants: comparative pharmacology with vitamin K antagonists.

Authors:  Francesco Scaglione
Journal:  Clin Pharmacokinet       Date:  2013-02       Impact factor: 6.447

6.  Apixaban metabolism and pharmacokinetics after oral administration to humans.

Authors:  Nirmala Raghavan; Charles E Frost; Zhigang Yu; Kan He; Haiying Zhang; W Griffith Humphreys; Donald Pinto; Shiangyuan Chen; Samuel Bonacorsi; Pancras C Wong; Donglu Zhang
Journal:  Drug Metab Dispos       Date:  2008-10-02       Impact factor: 3.922

Review 7.  New Direct Oral Anticoagulants (DOAC) and Their Use Today.

Authors:  Heike Schwarb; Dimitrios A Tsakiris
Journal:  Dent J (Basel)       Date:  2016-03-11
  7 in total

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