Marcus J Drake1, Paul Abrams2, Athene Lane3, Amanda L Lewis3. 1. Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK; Bristol Urological Institute, North Bristol NHS Trust, Bristol, UK. Electronic address: marcus.drake@bui.ac.uk. 2. Bristol Urological Institute, North Bristol NHS Trust, Bristol, UK. 3. Bristol Randomised Trials Collaboration, Bristol Trials Centre, University of Bristol, Bristol, UK; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.