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Literature DB >> 32900357

Theranostics of Metastatic Prostate Cancer Applying ⁶⁴Cu/¹⁸F/⁶⁸Ga PSMA PET-CT and ¹⁷⁷Lu Radiopharmaceuticals.

Siroos Mirzaei¹, Fairoz Mohammed¹, Shahin Zandieh².

Abstract

The successful use of theranostic twins in neuroendocrine tumors (NET) is the pioneering approach to radionuclide therapy in other tumor types. 64Cu/18F PSMA for molecular imaging with PET-CT and peptide radioligand therapy (PRLT) with 177Lu labeled PSMA inhibitors are the next theranostic twins in nuclear medicine. 68Ga/ 64Cu/18F PSMA PET-CT detects metastatic prostate cancer with high diagnostic sensitivity and specificity and can be used to select patients for PRLT and evaluate therapy response. Radionuclide therapy with 177Lu-PSMA inhibitors has been shown to be effective in the treatment of metastatic CRPC. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities: Chemical

Keywords: 64CuCl2; CRPC; NET; PET-CT; Peptide radioligand therapy; glioblastoma; melanoma.; prostate cancer

Mesh：

Substances：

Year: 2021 PMID： 32900357 DOI： 10.2174/1874471013666200908122845

Source DB: PubMed Journal: Curr Radiopharm ISSN： 1874-4710

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Cited

3 in total

1. High value of ⁶⁴Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson's disease.

Authors: Oihana Murillo; Maria Collantes; Cristina Gazquez; Daniel Moreno; Ruben Hernandez-Alcoceba; Miren Barberia; Margarita Ecay; Blanche Tamarit; Anne Douar; Veronica Ferrer; Jean Philippe Combal; Ivan Peñuelas; Bernard Bénichou; Gloria Gonzalez-Aseguinolaza
Journal: Mol Ther Methods Clin Dev Date: 2022-06-09 Impact factor: 5.849

2. Soft tissue metastasis of the penis detected by copper-64 labeled prostate-specific membrane antigen positron emission tomography (⁶⁴Cu-PSMA PET/CT) in a patient with prostate cancer.

Authors: Cherin Farhan; Siroos Mirzaei
Journal: Asia Ocean J Nucl Med Biol Date: 2021

Review 3. Implications of physics, chemistry and biology for dosimetry calculations using theranostic pairs.

Authors: Cassandra Miller; Julie Rousseau; Caterina F Ramogida; Anna Celler; Arman Rahmim; Carlos F Uribe
Journal: Theranostics Date: 2022-01-01 Impact factor: 11.600

3 in total

Theranostics of Metastatic Prostate Cancer Applying 64Cu/18F/68Ga PSMA PET-CT and 177Lu Radiopharmaceuticals.

1. High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson's disease.

2. Soft tissue metastasis of the penis detected by copper-64 labeled prostate-specific membrane antigen positron emission tomography (64Cu-PSMA PET/CT) in a patient with prostate cancer.

Review 3. Implications of physics, chemistry and biology for dosimetry calculations using theranostic pairs.

Theranostics of Metastatic Prostate Cancer Applying ⁶⁴Cu/¹⁸F/⁶⁸Ga PSMA PET-CT and ¹⁷⁷Lu Radiopharmaceuticals.

1. High value of ⁶⁴Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson's disease.

2. Soft tissue metastasis of the penis detected by copper-64 labeled prostate-specific membrane antigen positron emission tomography (⁶⁴Cu-PSMA PET/CT) in a patient with prostate cancer.