Literature DB >> 32896806

Lung cancer recurrence and mortality outcomes over a 10-year period using a multidisciplinary team approach.

Barbara Nemesure1, Denise Albano2, Thomas Bilfinger3.   

Abstract

BACKGROUND: Longitudinal data are limited regarding the impact of a multidisciplinary team (MDT) approach on patient outcomes among those diagnosed with lung cancer. The purpose of this study is to 1) compare 1- and 3-year recurrence and mortality rates among patients receiving a MDT vs. standard model of care; and 2) assess trends in these proportions over a 10-year period.
METHODS: This investigation included 2044 lung cancer cases reported to the Stony Brook Cancer Registry between 2006 and 2015. Patients were stratified into 2 groups, those participating in Stony Brook's Lung Cancer Evaluation Center's (LCEC) MDT Program (n = 1179) and those receiving a standard model of care (n = 865). 1- and 3-year stage-stratified recurrence and mortality rates are reported. Logistic regression analyses are performed and linear by linear associations are used to assess trends over time.
RESULTS: A higher proportion of patients in the MDT program (LCEC) remained disease-free at 1-year compared those receiving standard care (80.0 % vs 62.3 %, p < 0.01). There were no significant changes in mortality over the 10-year observation period in either group, however the rates were significantly lower among LCEC vs non-LCEC cases after adjusting for possible confounders (OR = 0.68 (0.51,0.90) at 1-year; OR = 0.50 (0.36, 0.70) at 3-years). Recurrence was also lower at 3-years in the MDT group (OR = 0.51 (0.32, 0.79)).
CONCLUSIONS: This study suggests that a comprehensive MDT program for lung cancer yields improved patient outcomes compared to the standard model of care and this approach may help to decrease rates of disease recurrence and mortality.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Lung cancer; Mortality; Multidisciplinary; Recurrence; Time trends

Year:  2020        PMID: 32896806     DOI: 10.1016/j.canep.2020.101804

Source DB:  PubMed          Journal:  Cancer Epidemiol        ISSN: 1877-7821            Impact factor:   2.984


  1 in total

1.  Association between physical activity and health-related quality of life: time to deterioration model analysis in lung adenocarcinoma.

Authors:  Jinman Zhuang; Yuhang Liu; Xinying Xu; Yuxin Cai; Maolin Liu; Zishan Chen; Shuyan Yang; Jianbo Lin; Zhijian Hu; Mingqiang Kang; Mengxin Lin; Fei He
Journal:  J Cancer Surviv       Date:  2022-10-04       Impact factor: 4.062

  1 in total

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