Literature DB >> 32894641

Lung transplantation during the COVID-19 pandemic: Safely navigating the new "normal".

Samantha E Halpern1, Danae G Olaso1, Madison K Krischak1, John M Reynolds2, John C Haney3, Jacob A Klapper3, Matthew G Hartwig3.   

Abstract

In the United States, an overall national decline in organ transplants has accompanied the substantial burden of COVID-19. Amidst significant regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation. Our LTx practice during the early pandemic may provide a blueprint for managing LTx in an era of continued community prevalence. Patients who underwent LTx at our institution between March 1 and May 20, 2020 were included. Recipient, operative, and donor characteristics were compared to those from our program in 2019, and COVID-19 testing practices were evaluated for March, April, and May to understand how our practice adapted to the pandemic. Our program performed 36 LTx, 33% more than the same period in 2019. Recipient, operative, and donor characteristics during COVID-19 were similar to those in 2019. By April 1, all donors and recipients underwent pretransplant COVID-19 testing, all returning negative results. To date, no recipients have developed posttransplant COVID-19. At our institution, pretransplant COVID-19 testing, use of local donor lungs, and avoidance of donors from areas of increased community penetration supported a safe and effective LTx practice during the early COVID-19 pandemic. Continued follow-up is required to ensure the long-term safety of these newly transplanted patients.
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Mesh:

Year:  2020        PMID: 32894641     DOI: 10.1111/ajt.16304

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  3 in total

Review 1.  How COVID-19 Affects Lung Transplantation: A Comprehensive Review.

Authors:  Jiri Vachtenheim; Rene Novysedlak; Monika Svorcova; Robert Lischke; Zuzana Strizova
Journal:  J Clin Med       Date:  2022-06-18       Impact factor: 4.964

2.  Editorial: COVID-19 immunology and organ transplantation.

Authors:  Amit I Bery; Hrishikesh S Kulkarni; Daniel Kreisel
Journal:  Curr Opin Organ Transplant       Date:  2021-04-01       Impact factor: 2.640

3.  Clinical Practice Guideline for Solid Organ Donation and Transplantation During the COVID-19 Pandemic.

Authors:  Matthew J Weiss; Laura Hornby; Farid Foroutan; Sara Belga; Simon Bernier; Mamatha Bhat; C Arianne Buchan; Michael Gagnon; Gillian Hardman; Maria Ibrahim; Cindy Luo; Me-Linh Luong; Rahul Mainra; Alex R Manara; Ruth Sapir-Pichhadze; Sarah Shalhoub; Tina Shaver; Jeffrey M Singh; Sujitha Srinathan; Ian Thomas; Lindsay C Wilson; T Murray Wilson; Alissa Wright; Allison Mah
Journal:  Transplant Direct       Date:  2021-09-07
  3 in total

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