Literature DB >> 32892657

What are the practical, ethical, and pathobiological considerations in the use of minipigs as an animal model in drug discovery for acute radiation syndrome and delayed effects of acute radiation exposure?

Doreswamy Kenchegowda1,2, Thomas M Seed3, Vijay K Singh1,2.   

Abstract

Entities:  

Keywords:  Animal models; drug discovery; ethical considerations; minipig; nonhuman primates; radiation countermeasures

Year:  2020        PMID： 32892657     DOI： 10.1080/17460441.2020.1811671

Source DB:  PubMed          Journal:  Expert Opin Drug Discov        ISSN： 1746-0441            Impact factor:   6.098


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  1 in total

1.  Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome.

Authors:  W Bradley Rittase; Elizabeth A McCart; Jeannie M Muir; Roxane M Bouten; John E Slaven; Ognoon Mungunsukh; Michelle A Bylicky; W Louis Wilkins; Sang-Ho Lee; Kristbjorn O Gudmundsson; Tiziana Di Pucchio; Cara H Olsen; Yang Du; Regina M Day
Journal:  PLoS One       Date:  2021-08-27       Impact factor: 3.240
  1 in total

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