Hiral Master1,2, Jacquelyn S Pennings1,2, Rogelio A Coronado1,2,3, Abigail L Henry1, Michael T O'Brien1, Christine M Haug1, Richard L Skolasky4, Lee H Riley4, Brian J Neuman4, Joseph S Cheng5, Oran S Aaronson6, Clinton J Devin1,7, Stephen T Wegener8, Kristin R Archer1,2,3. 1. Department of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN. 2. Center for Musculoskeletal Research, Vanderbilt University Medical Center, Nashville, TN. 3. Department of Physical Medicine and Rehabilitation, Osher Center for Integrative Medicine, Vanderbilt University Medical Center, Nashville, TN. 4. Department of Orthopedic Surgery, Johns Hopkins Medicine, Baltimore, MD. 5. Department of Neurological Surgery, University of Cincinnati College of Medicine, Cincinnati, OH. 6. Howell Allen Clinic, Saint Thomas Medical Partners, Nashville, TN. 7. Steamboat Orthopedic and Spine Institute, Steamboat Springs, CO. 8. Department of Physical Medicine and Rehabilitation, Johns Hopkins Medicine, Baltimore, MD.
Abstract
STUDY DESIGN: Secondary analysis of randomized controlled trial data. OBJECTIVE: The aim of this study was to examine whether preoperative physical performance is an independent predictor of patient-reported disability and pain at 12 months after lumbar spine surgery. SUMMARY OF BACKGROUND DATA: Patient-reported outcome measures (PROMs) are commonly used to assess clinical improvement after lumbar spine surgery. However, there is evidence in the orthopedic literature to suggest that PROMs should be supplemented with physical performance tests to accurately evaluate long-term outcomes. METHODS: A total of 248 patients undergoing surgery for degenerative lumbar spine conditions were recruited from two institutions. Physical performance tests (5-Chair Stand and Timed Up and Go) and PROMs of disability (Oswestry Disability Index: ODI) and back and leg pain (Brief Pain Inventory) were assessed preoperatively and at 12 months after surgery. RESULTS:Physical performance tests and PROMs significantly improved over 12 months following lumbar spine surgery (P < 0.01). Weak correlations were found between physical performance tests and disability and pain (ρ = 0.15 to 0.32, P < 0.05). Multivariable regression analyses controlling for age, education, preoperative outcome score, fusion, previous spine surgery, depressive symptoms, and randomization group found that preoperative 5-Chair Stand test was significantly associated with disability and back pain at 12-month follow-up. Each additional 10 seconds needed to complete the 5-Chair Stand test were associated with six-point increase in ODI (P = 0.047) and one-point increase in back pain (P = 0.028) scores. The physical performance tests identified an additional 14% to 19% of patients as achieving clinical improvement that were not captured by disability or pain questionnaires. CONCLUSION: Results indicate that physical performance tests may provide distinct information in both predicting and assessing clinical outcomes in patients undergoing lumbar spine surgery. Our findings suggest that the 5-Chair Stand test may be a useful test to include within a comprehensive risk assessment before surgery and as an outcome measure at long-term follow-up. LEVEL OF EVIDENCE: 3.
RCT Entities:
STUDY DESIGN: Secondary analysis of randomized controlled trial data. OBJECTIVE: The aim of this study was to examine whether preoperative physical performance is an independent predictor of patient-reported disability and pain at 12 months after lumbar spine surgery. SUMMARY OF BACKGROUND DATA: Patient-reported outcome measures (PROMs) are commonly used to assess clinical improvement after lumbar spine surgery. However, there is evidence in the orthopedic literature to suggest that PROMs should be supplemented with physical performance tests to accurately evaluate long-term outcomes. METHODS: A total of 248 patients undergoing surgery for degenerative lumbar spine conditions were recruited from two institutions. Physical performance tests (5-Chair Stand and Timed Up and Go) and PROMs of disability (Oswestry Disability Index: ODI) and back and leg pain (Brief Pain Inventory) were assessed preoperatively and at 12 months after surgery. RESULTS: Physical performance tests and PROMs significantly improved over 12 months following lumbar spine surgery (P < 0.01). Weak correlations were found between physical performance tests and disability and pain (ρ = 0.15 to 0.32, P < 0.05). Multivariable regression analyses controlling for age, education, preoperative outcome score, fusion, previous spine surgery, depressive symptoms, and randomization group found that preoperative 5-Chair Stand test was significantly associated with disability and back pain at 12-month follow-up. Each additional 10 seconds needed to complete the 5-Chair Stand test were associated with six-point increase in ODI (P = 0.047) and one-point increase in back pain (P = 0.028) scores. The physical performance tests identified an additional 14% to 19% of patients as achieving clinical improvement that were not captured by disability or pain questionnaires. CONCLUSION: Results indicate that physical performance tests may provide distinct information in both predicting and assessing clinical outcomes in patients undergoing lumbar spine surgery. Our findings suggest that the 5-Chair Stand test may be a useful test to include within a comprehensive risk assessment before surgery and as an outcome measure at long-term follow-up. LEVEL OF EVIDENCE: 3.
Authors: Ramin Fallahzadeh; Franck Verdonk; Ed Ganio; Anthony Culos; Natalie Stanley; Ivana Marić; Alan L Chang; Martin Becker; Thanaphong Phongpreecha; Maria Xenochristou; Davide De Francesco; Camilo Espinosa; Xiaoxiao Gao; Amy Tsai; Pervez Sultan; Martha Tingle; Derek F Amanatullah; James I Huddleston; Stuart B Goodman; Brice Gaudilliere; Martin S Angst; Nima Aghaeepour Journal: Ann Surg Date: 2021-10-08 Impact factor: 13.787