| Literature DB >> 32883082 |
Michael R Stentzel1, Douglas A Klumpp1.
Abstract
The conjugate addition reactions of trans-1,2-di(2-pyridyl)ethylene have been studied. This substrate reacts with organolithium nucleophiles, and the resulting anionic intermediates may be trapped by proton or various carbonyl-based electrophiles. It is suggested that the dipyridyl structure stabilizes the intermediate carbanion, allowing the Michael adduct to be captured by an added electrophile.Entities:
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Year: 2020 PMID： 32883082 PMCID： PMC7781395 DOI： 10.1021/acs.joc.0c00823
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354