Literature DB >> 32877817

White learning methodology: A case study of cancer-related disease factors analysis in real-time PACS environment.

Tengyue Li1, Simon Fong2, Shirley W I Siu3, Xin-She Yang4, Lian-Sheng Liu5, Sabah Mohammed6.   

Abstract

BACKGROUND AND
OBJECTIVE: Bayesian network is a probabilistic model of which the prediction accuracy may not be one of the highest in the machine learning family. Deep learning (DL) on the other hand possess of higher predictive power than many other models. How reliable the result is, how it is deduced, how interpretable the prediction by DL mean to users, remain obscure. DL functions like a black box. As a result, many medical practitioners are reductant to use deep learning as the only tool for critical machine learning application, such as aiding tool for cancer diagnosis.
METHODS: In this paper, a framework of white learning is being proposed which takes advantages of both black box learning and white box learning. Usually, black box learning will give a high standard of accuracy and white box learning will provide an explainable direct acyclic graph. According to our design, there are 3 stages of White Learning, loosely coupled WL, semi coupled WL and tightly coupled WL based on degree of fusion of the white box learning and black box learning. In our design, a case of loosely coupled WL is tested on breast cancer dataset. This approach uses deep learning and an incremental version of Naïve Bayes network. White learning is largely defied as a systemic fusion of machine learning models which result in an explainable Bayes network which could find out the hidden relations between features and class and deep learning which would give a higher accuracy of prediction than other algorithms. We designed a series of experiments for this loosely coupled WL model.
RESULTS: The simulation results show that using WL compared to standard black-box deep learning, the levels of accuracy and kappa statistics could be enhanced up to 50%. The performance of WL seems more stable too in extreme conditions such as noise and high dimensional data. The relations by Bayesian network of WL are more concise and stronger in affinity too.
CONCLUSION: The experiments results deliver positive signals that WL is possible to output both high classification accuracy and explainable relations graph between features and class.
Copyright © 2020. Published by Elsevier B.V.

Entities:  

Keywords:  Bayesian network; Data mining methodology; Deep learning; Radiological data analysis

Mesh:

Year:  2020        PMID: 32877817     DOI: 10.1016/j.cmpb.2020.105724

Source DB:  PubMed          Journal:  Comput Methods Programs Biomed        ISSN: 0169-2607            Impact factor:   5.428


  2 in total

Review 1.  [Use of medical archives for research and patient care].

Authors:  M Peredin; S Baur
Journal:  Urologe A       Date:  2021-12-22       Impact factor: 0.639

2.  Toward Modeling Psychomotor Performance in Karate Combats Using Computer Vision Pose Estimation.

Authors:  Jon Echeverria; Olga C Santos
Journal:  Sensors (Basel)       Date:  2021-12-15       Impact factor: 3.576

  2 in total

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