| Literature DB >> 32875879 |
Ashley R Strickland1, M Farooq Usmani1, Jael E Camacho1, Amil Sahai1, Jacob J Bruckner1, Kendall Buraimoh1, Eugene Y Koh1, Daniel E Gelb1, Steven C Ludwig1.
Abstract
STUDYEntities:
Keywords: degenerative; length of stay; low back pain; lumbar; narcotic use; postoperative complication; urinary retention
Year: 2020 PMID: 32875879 PMCID: PMC8013941 DOI: 10.1177/2192568220904681
Source DB: PubMed Journal: Global Spine J ISSN: 2192-5682
Figure 1.Patient inclusion and exclusion into the study. A total of 586 patients were identified from the database and 217 were included in the study.
Abbreviations: EMR, electronic medical record; ESRD, end-stage renal disease.
Figure 2.Foley catheter removal protocol: after 2 I&O catheterizations, the Foley catheter is reinserted and the patient is started on tamsulosin.
Abbreviations: I&O, in and out; TOV, trial of void; PVR, postvoid residual scan; DRE, digital rectal examination.
Patient Demographic Characteristics and Comorbidities.
| Number of patients | 217 |
| Age (mean ± SD) | 61.3 ± 10.3 |
| BMI (mean ± SD) | 30.9 ± 6.7 |
| Sex (male), n (%) | 98 (45.2) |
| Previous lumbar surgery, n (%) | 106 (48.9) |
| Diagnosis, n (%) | |
| Spondylolisthesis | 92 (42.4) |
| Spinal stenosis | 79 (36.4) |
| Degenerative scoliosis | 31 (14.3) |
| Positive sagittal balance | 8 (3.7) |
| Others | 7 (3.2) |
| Comorbid conditions, n (%) | |
| Hypertension | 115 (53.0) |
| Hyperlipidemia | 90 (41.5) |
| Depression | 56 (25.8) |
| Smoker (current)a | 37 (17.1) |
| Smoker (former)b | 55 (25.4) |
| Diabetes | 45 (20.7) |
| OSA | 37 (17.1) |
| UTI | 27 (12.5) |
| CAD | 25 (11.5) |
| Prior opioid use | 21 (9.7) |
| COPD | 12 (5.5) |
| BPH | 10 (4.6) |
a Smoker (current): quit less than 1 year ago.
b Smoker (Former): Quit more than 1 year ago.
Abbreviations: BMI, body mass index; OSA, obstructive sleep apnea; UTI, urinary tract infection; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; BPH, benign prostate hyperplasia.
Patient Surgical Characteristics.
| Number of patients | 217 |
| Levels fused, n (%) | |
| One | 21 (9.7) |
| Two | 122 (56.2) |
| Three | 28 (12.9) |
| Four | 26 (12.0) |
| Five | 9 (4.1) |
| Six or more | 11 (5.1) |
| Surgical approach used, n (%) | |
| Posterior | 195 (89.8) |
| Anterior | 14 (6.5) |
| Combined | 8 (3.7) |
| Intraoperative details, n (%) | |
| Bone morphogenetic protein use | 15 (6.9) |
| Dural tear | 25 (11.5) |
Comparison of Characteristics Between Patients With and Without Postoperative Urinary Retention (POUR).
| Characteristics | No POUR | POUR | |
|---|---|---|---|
| Number of patients | 163 | 54 | |
| Age (mean ± SD) | 59.4 ± 10.0 | 67.0 ± 9.3 | <.0001a |
| BMI (mean ± SD) | 31.0 ± 6.7 | 30.9 ± 6.7 | .97 |
| Sex (male), n (%) | 74 (45.4) | 24 (44.4) | 1.00 |
| Previous lumbar surgery, n (%) | 82 (50.3) | 24 (44.4) | .53 |
| Diagnosis, n (%) | .25 | ||
| Spondylolisthesis | 71 (43.6) | 21 (38.9) | |
| Spinal stenosis | 63 (38.7) | 16 (29.6) | |
| Degenerative scoliosis | 20 (12.3) | 11 (20.4) | |
| Positive sagittal balance | 4 (2.5) | 4 (7.4) | |
| Others | 5 (3.1) | 2 (3.7) | |
| Comorbid conditions, n (%) | |||
| Diabetes | 31 (19.0) | 14 (25.9) | .33 |
| Depression | 47 (28.8) | 9 (16.7) | .11 |
| Smoker (current)b | 40 (24.5) | 15 (27.8) | 1.00 |
| Smoker (former)c | 28 (17.2) | 9 (16.7) | .72 |
| BPH (only males) | 6 (8.1) | 4 (16.7) | .25 |
| Hyperlipidemia | 65 (39.9) | 25 (46.3) | .42 |
| Hypertension | 22 (13.5) | 5 (9.3) | .12 |
| UTI | 81 (49.7) | 34 (63.0) | .48 |
| CAD | 16 (9.8) | 9 (16.7) | .22 |
| COPD | 10 (6.1) | 2 (3.7) | .73 |
| OSA | 26 (16.0) | 11 (20.4) | .53 |
| Prior opioid use | 15 (9.2) | 6 (11.1) | .68 |
Abbreviations: BMI, body mass index; BPH, benign prostate hyperplasia; UTI, urinary tract infection; CAD, coronary artery disease; COPD, chronic obstructive pulmonary disease; OSA, obstructive sleep apnea.
a Statistically significant, with P value <.05.
b Smoker (current): quit less than 1 year ago.
c Smoker (former): quit more than 1 year ago.
Comparison of Surgical Details for Patients With and Without Postoperative Urinary Retention (POUR).
| Surgical Details | No POUR | POUR | |
|---|---|---|---|
| Number of patients | 163 | 54 | |
| Levels fused, n (%)a | .01b | ||
| One | 21 (12.9) | 0 (0) | .0026b |
| Two | 91 (55.8) | 31 (57.4) | .875 |
| Three | 21 (12.9) | 7 (13.0) | 1.00 |
| Four | 18 (11.0) | 8 (14.8) | .47 |
| Five | 7 (4.3) | 2 (3.7) | 1.00 |
| Six or more | 5 (3.1) | 6 (11.1) | .03b |
| Surgical approach used, n (%) | .36 | ||
| Posterior | 144 (88.3) | 51 (94.4) | |
| Anterior | 13 (8.0) | 1 (1.9) | |
| Both | 6 (3.7) | 2 (3.7) | |
| Construct details, n (%) | |||
| BMP | 11 (6.7) | 4 (7.6) | 1.00 |
| Dural tear | 18 (11.0) | 7 (13.0) | .81 |
| Intraoperative details (mean ± SD) | |||
| Length of surgery (minutes) | 216 ± 82 | 218 ± 100 | .89 |
| Fluids (mL)c | 3403 ± 1636 | 3689 ± 1781 | .29 |
| Albumin (5% or 25%) (mL) | 137 ± 223 | 188 ± 287 | .24 |
| EBL (mL) | 741 ± 786 | 866 ± 883 | .36 |
| Urine output (mL) | 541 ± 420 | 651 ± 513 | .16 |
| pRBCs transfused (Units)d | 0.44 ± 1.31 | 0.89 ± 2.39 | .20 |
| Cell saver (mL) | 22 ± 110 | 19 ± 78 | .82 |
Abbreviations: ASA, American Society of Anesthesiologists Classification System; BMP, bone morphogenetic protein; EBL, Estimated Blood Loss; pRBCs, packed red blood cells.
a Post hoc analysis was done with multiple Fisher exact tests, and statistical significance was assessed after α was corrected using the Bonferroni correction [(α = 0.05)/6 = 0.008].
b Statistically significant with P value <.05.
c Fluids used includes PlasmaLyte A, Normal Saline, Lactated Ringers.
d pRBCs used for 48 patients.
Comparison of Drugs Used in Anesthesia for Patients With and Without Postoperative Urinary Retention (POUR).
| Surgical Details | Total | No POUR | POUR | |
|---|---|---|---|---|
| Number of patients | 257 | 163 | 54 | |
| ASA class,a n (%) | .31 | |||
| Two | 107 (50.0) | 85 (52.8) | 22 (41.5) | |
| Three | 103 (48.1) | 73 (45.3) | 30 (56.6) | |
| Drugs used, n (%) | ||||
| Propofol | 215 (99.1) | 162 (99.4) | 53 (98.1) | .44 |
| Fentanyl | 210 (96.8) | 158 (96.9) | 52 (96.3) | 1 |
| Rocuronium | 197 (90.8) | 150 (92.0) | 47 (87.0) | .28 |
| Midazolam | 158 (72.8) | 119 (73.0) | 39 (72.2) | 1 |
| Hydromorphone | 135 (62.2) | 103 (63.2) | 32 (59.3) | .63 |
| Remifentanil | 88 (40.6) | 67 (41.1) | 21 (38.9) | .87 |
| Dexamethasone | 84 (38.7) | 66 (40.5) | 18 (33.3) | .43 |
| Glycopyrrolate | 81 (37.3) | 60 (36.8) | 21 (38.9) | .87 |
| Methadone | 50 (23.0) | 39 (23.9) | 11 (20.4) | .71 |
| Sugammadex | 37 (17.1) | 28 (17.2) | 9 (16.7) | 1 |
| Ketamine | 31 (14.3) | 24 (14.7) | 7 (13.0) | 0.82 |
Abbreviations: ASA, American Society of Anesthesiologists Classification System.
a Only shown for patients with ASA of 2 or 3.
Comparison of Postoperative Stay for Patients With and Without Postoperative Urinary Retention (POUR).
| Surgical Details | No POUR | POUR | |
|---|---|---|---|
| Number of patients | 164 | 54 | |
| Length of stay, mean ± SD | 4.9 ± 3.9 | 5.8 ± 3.3 | .039a |
| Foley removal (day), mean ± SD | 2.3 ± 1.3 | 2.3 ± 1.2 | .84 |
| Patient-controlled analgesia, n | 155 | 54 | .21 |
| Urinary retention | |||
| Volume on bladder scan (mL), mean ± SD | — | 374 ± 242 | |
| Post void residual (mL), mean ± SD | — | 225 ± 280 |
a Statistically significant with P value <.05.