Naoya Ishibashi1, Toshiya Maebayashi2, Haruna Nishimaki3, Masahiro Okada2. 1. Department of Radiology, Nihon University School of Medicine, Tokyo, Japan ishibashi.naoya@nihon-u.ac.jp. 2. Department of Radiology, Nihon University School of Medicine, Tokyo, Japan. 3. Department of Oncologic Pathology, Nihon University School of Medicine, Tokyo, Japan.
Abstract
BACKGROUND: Computed tomography (CT) performed after radiation therapy (RT) is used to detect residual lymph node (LN) metastasis. Here, we investigated which LN parameters on pre- and post-RT CT images correlated with residual tumour in patients with head and neck cancer. PATIENTS AND METHODS: We enrolled 23 patients who received RT. A total of 50 LNs were evaluated. Correlations between quantitative and qualitative findings and residual tumours were evaluated. RESULTS: The median patient age was 61 years. Thirty-one LNs were histologically confirmed to contain residual tumour. LNs with residual tumour had significantly longer short and long axes on post-RT CT images. A new finding of obscured margins after RT were significantly associated with the presence of residual tumour by univariate and multivariate analyses. CONCLUSION: Comparison of qualitative, LN parameters on pre- and post-RT CT images may improve the detection of residual tumour in patients with suspected residual or recurrent LN metastasis. Copyright
BACKGROUND: Computed tomography (CT) performed after radiation therapy (RT) is used to detect residual lymph node (LN) metastasis. Here, we investigated which LN parameters on pre- and post-RT CT images correlated with residual tumour in patients with head and neck cancer. PATIENTS AND METHODS: We enrolled 23 patients who received RT. A total of 50 LNs were evaluated. Correlations between quantitative and qualitative findings and residual tumours were evaluated. RESULTS: The median patient age was 61 years. Thirty-one LNs were histologically confirmed to contain residual tumour. LNs with residual tumour had significantly longer short and long axes on post-RT CT images. A new finding of obscured margins after RT were significantly associated with the presence of residual tumour by univariate and multivariate analyses. CONCLUSION: Comparison of qualitative, LN parameters on pre- and post-RT CT images may improve the detection of residual tumour in patients with suspected residual or recurrent LN metastasis. Copyright
Authors: Christian Simon; Helmuth Goepfert; David I Rosenthal; Dianna Roberts; Adel El-Naggar; Matthew Old; Eduardo M Diaz; Jeffrey N Myers Journal: Eur Arch Otorhinolaryngol Date: 2005-11-22 Impact factor: 2.503
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