Ioannis D Kostakis1, Themistoklis Feretis2, Christos Damaskos3,4, Nikolaos Garmpis4,5, George Liapis6, Ioannis Pateras6, Anna Garmpi7, Vasiliki E Georgakopoulou8,9, Efstathios A Antoniou4,5. 1. Department of Transplantation, Guy's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, U.K. 2. First Department of Endoscopic Surgery, Metropolitan General Hospital, Athens, Greece. 3. Renal Transplantation Unit, Laiko General Hospital, Athens, Greece x_damaskos@yahoo.gr. 4. N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 5. Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 6. First Department of Pathology, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 7. First Department of Propedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 8. Department of Pulmonology, Laiko General Hospital, Athens, Greece. 9. First Department of Pulmonology, Sismanogleio Hospital, Athens, Greece.
Abstract
BACKGROUND: Nuchal-type fibroma is a rare benign tumor arising from the connective tissue. Our aim was to present our experience via two cases of this tumor and a comprehensive review of the literature. PATIENTS AND METHODS: We report a case of a 23-year-old female with a mass located in the posterior neck and the upper back and a case of a 50-year-old male with a mass located in the posterior neck, which were proved to be nuchal-type fibromas in the histopathological examination. We also searched the PubMed/Medline database for published cases of nuchal-type fibromas. RESULTS AND DISCUSSION: Nuchal-type fibroma is a rare benign tumor arising from the connective tissue, usually in the posterior neck, which affects different ages, with most patients being male. It is a poorly circumscribed tumor consisting of hypocellular, thick, dense and haphazardly arranged collagen bundles with entrapped adipocytes, nerve fibers and muscle fascicles and a few scattered spindle cells, which are CD34 positive. Its excision is curative, and the recurrence risk is generally low. However, patients with Gardner's syndrome may experience recurrence more frequently. CONCLUSION: Nuchal-type fibroma should be included in the differential diagnosis of subcutaneous, soft-tissue masses, especially when these involve the posterior neck. Copyright
BACKGROUND:Nuchal-type fibroma is a rare benign tumor arising from the connective tissue. Our aim was to present our experience via two cases of this tumor and a comprehensive review of the literature. PATIENTS AND METHODS: We report a case of a 23-year-old female with a mass located in the posterior neck and the upper back and a case of a 50-year-old male with a mass located in the posterior neck, which were proved to be nuchal-type fibromas in the histopathological examination. We also searched the PubMed/Medline database for published cases of nuchal-type fibromas. RESULTS AND DISCUSSION: Nuchal-type fibroma is a rare benign tumor arising from the connective tissue, usually in the posterior neck, which affects different ages, with most patients being male. It is a poorly circumscribed tumor consisting of hypocellular, thick, dense and haphazardly arranged collagen bundles with entrapped adipocytes, nerve fibers and muscle fascicles and a few scattered spindle cells, which are CD34 positive. Its excision is curative, and the recurrence risk is generally low. However, patients with Gardner's syndrome may experience recurrence more frequently. CONCLUSION:Nuchal-type fibroma should be included in the differential diagnosis of subcutaneous, soft-tissue masses, especially when these involve the posterior neck. Copyright
Authors: A Hernández-Núñez; J C Tardío; V M Castellano-Megias; A Romero-Maté; J Borbujo Journal: J Eur Acad Dermatol Venereol Date: 2007-11 Impact factor: 6.166
Authors: Patrick Kiessling; Eric Dowling; Yajue Huang; Mai Lan Ho; Karthik Balakrishnan; Brenda J Weigel; W Edward Highsmith; Zhiyv Niu; Lisa A Schimmenti Journal: Cold Spring Harb Mol Case Stud Date: 2019-04-01