K Drareni1,2, M Bensafi3, A Giboreau4, A Dougkas4. 1. Institut Paul Bocuse Research Centre, 1, Chemin de Calabert, 69130, Ecully Cedex, France. Kenza.drareni@institutpaulbocuse.com. 2. CNRS, UMR5292, INSERM U1028, Lyon Neuroscience Research Center, University of Lyon, Lyon, France. Kenza.drareni@institutpaulbocuse.com. 3. CNRS, UMR5292, INSERM U1028, Lyon Neuroscience Research Center, University of Lyon, Lyon, France. 4. Institut Paul Bocuse Research Centre, 1, Chemin de Calabert, 69130, Ecully Cedex, France.
Abstract
PURPOSE: Chemotherapy-induced taste and smell alterations may have a negative impact on the quality of life and nutritional status. A prominent issue when dealing with taste and smell alterations and their consequences on food behavior and well-being lies in the variation arising from individual differences in chemosensory perceptions. The main aim of this study was to examine the effect of individuals' variation in the severity of taste and smell alterations relative to the stage of chemotherapy on self-reported food behavior and food perception. METHODS: Eighty-nine cancer patients completed a questionnaire subdivided into two parts: a chemosensory part that allowed classification of patients in three groups ("no alterations," "moderate alterations," and "severe alterations") and a food behavior part. RESULTS: The results highlighted a negative impact of chemosensory alterations on food perception. Compared with patients without taste and smell alterations, patients with severe chemosensory alterations reported significantly more frequent food perception problems, including modification of the perceived taste of food, finding bad taste in all food, and being unable to perceive food taste. Whereas 72% of patients with severe alterations were in late stage, only 37% of patients were in late stage in the no alterations group, indicating an effect of the treatment stage on taste and smell alterations. CONCLUSION: Our results underlie the importance of providing specific attention to the severity of chemotherapy-induced taste and smell alterations and considering the individual differences among patients for a better nutritional management.
PURPOSE: Chemotherapy-induced taste and smell alterations may have a negative impact on the quality of life and nutritional status. A prominent issue when dealing with taste and smell alterations and their consequences on food behavior and well-being lies in the variation arising from individual differences in chemosensory perceptions. The main aim of this study was to examine the effect of individuals' variation in the severity of taste and smell alterations relative to the stage of chemotherapy on self-reported food behavior and food perception. METHODS: Eighty-nine cancerpatients completed a questionnaire subdivided into two parts: a chemosensory part that allowed classification of patients in three groups ("no alterations," "moderate alterations," and "severe alterations") and a food behavior part. RESULTS: The results highlighted a negative impact of chemosensory alterations on food perception. Compared with patients without taste and smell alterations, patients with severe chemosensory alterations reported significantly more frequent food perception problems, including modification of the perceived taste of food, finding bad taste in all food, and being unable to perceive food taste. Whereas 72% of patients with severe alterations were in late stage, only 37% of patients were in late stage in the no alterations group, indicating an effect of the treatment stage on taste and smell alterations. CONCLUSION: Our results underlie the importance of providing specific attention to the severity of chemotherapy-induced taste and smell alterations and considering the individual differences among patients for a better nutritional management.
Authors: Y C de Vries; M M G A van den Berg; J H M de Vries; S Boesveldt; J Th C M de Kruif; N Buist; A Haringhuizen; M Los; D W Sommeijer; J H N Timmer-Bonte; H W M van Laarhoven; M Visser; E Kampman; R M Winkels Journal: Support Care Cancer Date: 2017-03-16 Impact factor: 3.603
Authors: Marie Ernst Christensen; Anita Haahr; Pia Riis Olsen; Hanne Krogh Rose; Annelise Norlyk Journal: Int J Qual Stud Health Well-being Date: 2022-12
Authors: Nicole Kornbausch; Marcel W Debong; Andrea Buettner; Jean-Marie Heydel; Helene M Loos Journal: Angew Chem Int Ed Engl Date: 2022-07-28 Impact factor: 16.823
Authors: William M P Klein; Mary E O'Connell; Michele H Bloch; Susan M Czajkowski; Paige A Green; Paul K J Han; Richard P Moser; Linda C Nebeling; Robin C Vanderpool Journal: J Natl Cancer Inst Date: 2022-02-07 Impact factor: 13.506