Literature DB >> 3287009

Plants as sources of antimalarial drugs, Part 6: Activities of Simarouba amara fruits.

M J O'Neill1, D H Bray, P Boardman, C W Wright, J D Phillipson, D C Warhurst, M P Gupta, M Correya, P Solis.   

Abstract

Extracts prepared from Simarouba amara fruits collected in Panama have been found to be active against Plasmodium falciparum in vitro and against Plasmodium berghei in mice. Four active quassinoids have been identified as ailanthinone, 2'-acetylglaucarubinone, glaucarubinone and holacanthone.

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Year:  1988        PMID: 3287009     DOI: 10.1016/0378-8741(88)90126-2

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  2 in total

1.  Molecular mechanism of Escherichia coli H10407 induced diarrhoea and its control through immunomodulatory action of bioactives from Simarouba amara (Aubl.).

Authors:  Hegde Veena; Sandesh K Gowda; Rajeshwara N Achur; Nayaka Boramuthi Thippeswamy
Journal:  J Microbiol       Date:  2021-02-25       Impact factor: 3.422

2.  Oral acute and sub-chronic toxicity assessment of aqueous leaf extract of Simarouba glauca DC (Paradise tree).

Authors:  Sd E Osagie-Eweka; N E J Orhue; E K I Omogbai; F C Amaechina
Journal:  Toxicol Rep       Date:  2021-01-15
  2 in total

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