| Literature DB >> 32869702 |
Alexandre Candellier1,2, Anaïs Scohy3, Nicolas Gillet4, Benoit Muylkens4, Johann Morelle1, Leïla Belkhir5, Damien Coupeau4, Michel Jadoul1, Éric Goffin1.
Abstract
The pandemic of respiratory disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is life-threatening in peritoneal dialysis (PD) patients. In PD patients with systemic viral infections, peritoneal effluent may be theoretically contaminated. We searched for the presence of SARS-CoV-2 genetic material by real-time reverse transcriptase-polymerase chain reaction assays in serial PD effluents of three PD infected patients. Nasopharyngeal swabs obtained at admission showed high viral load in all three patients, whereas none of the PD effluent specimen tested positive, even after dialysate concentration. Those results support at most a very low SARS-CoV-2 dissemination risk by the peritoneal effluent of PD patients. Imposing special disposal procedures, such as the instillation of hypochlorite in the drainage bags to prevent viral spread to health-care workers, are probably not required.Entities:
Keywords: COVID-19; SARS-CoV-2; peritoneal dialysis; peritoneal effluent
Mesh:
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Year: 2020 PMID: 32869702 DOI: 10.1177/0896860820953061
Source DB: PubMed Journal: Perit Dial Int ISSN: 0896-8608 Impact factor: 1.756