Literature DB >> 3286866

Specific therapy in severe fetal intrauterine growth retardation: failure of prostacyclin.

S A Steel1, J M Pearce.   

Abstract

Two case histories of severe, early onset intrauterine growth retardation are presented. Intravenous prostacyclin was administered in an attempt to promote fetal growth and thus prolong the pregnancy, but was unsuccessful and resulted in intrauterine death in each case. The possible reasons for the failure of this treatment and alternative therapeutic options are discussed.

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Year:  1988        PMID: 3286866      PMCID: PMC1291543          DOI: 10.1177/014107688808100410

Source DB:  PubMed          Journal:  J R Soc Med        ISSN: 0141-0768            Impact factor:   18.000


  21 in total

Review 1.  Uteroplacental and fetal blood flow.

Authors:  J M Pearce
Journal:  Baillieres Clin Obstet Gynaecol       Date:  1987-03

2.  Qualitative assessment of uteroplacental blood flow: early screening test for high-risk pregnancies.

Authors:  S Campbell; J M Pearce; G Hackett; T Cohen-Overbeek; C Hernandez
Journal:  Obstet Gynecol       Date:  1986-11       Impact factor: 7.661

3.  Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants.

Authors:  T Y Khong; F De Wolf; W B Robertson; I Brosens
Journal:  Br J Obstet Gynaecol       Date:  1986-10

4.  Prevention of pre-eclampsia by early antiplatelet therapy.

Authors:  M Beaufils; S Uzan; R Donsimoni; J C Colau
Journal:  Lancet       Date:  1985-04-13       Impact factor: 79.321

5.  Depression and prostacyclin infusion.

Authors:  D Ansell; J J Belch; C D Forbes
Journal:  Lancet       Date:  1986-08-30       Impact factor: 79.321

6.  Fetal growth retardation and the arteries of the placental bed.

Authors:  I Brosens; H G Dixon; W B Robertson
Journal:  Br J Obstet Gynaecol       Date:  1977-09

7.  Doppler studies in the growth retarded fetus and prediction of neonatal necrotising enterocolitis, haemorrhage, and neonatal morbidity.

Authors:  G A Hackett; S Campbell; H Gamsu; T Cohen-Overbeek; J M Pearce
Journal:  Br Med J (Clin Res Ed)       Date:  1987-01-03

Review 8.  Prostacyclin and thromboxane in gynecology and obstetrics.

Authors:  O Ylikorkala; U M Mäkilä
Journal:  Am J Obstet Gynecol       Date:  1985-06-01       Impact factor: 8.661

9.  Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae.

Authors:  H C Wallenburg; G A Dekker; J W Makovitz; P Rotmans
Journal:  Lancet       Date:  1986-01-04       Impact factor: 79.321

10.  Dipyridamole and other phosphodiesterase inhibitors act as antithrombotic agents by potentiating endogenous prostacyclin.

Authors:  S Moncada; R Korbut
Journal:  Lancet       Date:  1978-06-17       Impact factor: 79.321

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