| Literature DB >> 32868100 |
Carla S Soares1, Pedro S Babo1, Rui L Reis1, Pedro P Carvalho2, Manuela E Gomes1.
Abstract
Platelet-derived products (PDPs) have gained popularity, mainly due to their high concentrations of bioactive molecules such as growth factors and cytokines, which play important roles in tissue healing and regeneration. PDPs are obtained through minimally invasive procedures and their therapeutic effect has been widely recognized. In veterinary medicine, however, the lack of standard protocols to generate PDPs is a major hurdle for assessing the clinical relevance of PDP-based therapies and for their widespread usage. The aim of this review is to analyze the technical and scientific specificities of PDPs in terms of preparation methodologies, classification categorization, nomenclature, and biological proprieties to advance their future biotechnological potential in veterinary contexts.Keywords: cytokines; fibrin; growth factors; platelet-therapy; regenerative medicine: nomenclature standardization
Year: 2020 PMID: 32868100 DOI: 10.1016/j.tibtech.2020.07.011
Source DB: PubMed Journal: Trends Biotechnol ISSN: 0167-7799 Impact factor: 19.536