Wenfang Yang1, Erli Wang2, Wenxiu Chen1, Chunming Chen1, Shanying Chen3. 1. Department of Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China. 2. Clinical Laboratory, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China. 3. Department of Nephrology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China, 1485744679@qq.com.
Abstract
BACKGROUND: Magnesium is an indispensable cation and plays an important physiological role in the body. Most previous studies focused on the single measurement of serum magnesium in patients undergoing hemodialysis. However, scant studies focused on continuous observations of serum magnesium levels. OBJECTIVE: To provide continuous observations of serum magnesium levels in patients on maintenance hemodialysis (MHD). The levels of magnesium in patients initiating hemodialysis are also recorded and analyzed in the present study. METHODS: In this retrospective study, we serially investigated the measurements of serum total magnesium in MHD patients and patients initiating hemodialysis. Our data were followed up for one year. We provided real-time update on the levels of serum magnesium in patients on hemodialysis. RESULTS: On January 1, 2019, a total of 356 end-stage renal disease patients were receiving hemodialysis in our hospital. On December 31, 2019, the number had increased to 383. We found that serum total magnesium levels were in the normal range before initiating hemodialysis. With the initiation of hemodialysis, the levels of serum total magnesium increased. In patients on MHD, hypermagnesemia was very common. Hypomagnesemia was rare when 0.5 mmol/L magnesium dialysate was used. We did not find proton pump inhibitor associated hypomagnesemia. CONCLUSION: We find that serum total magnesium levels are in the normal range before initiating hemodialysis. However, in patients on MHD, hypermagnesemia is common when 0.5 mmol/L magnesium dialysate is used. Hypomagnesemia is very rare. Hypomagnesemia in patients on MHD is an indicator of poor condition.
BACKGROUND:Magnesium is an indispensable cation and plays an important physiological role in the body. Most previous studies focused on the single measurement of serum magnesium in patients undergoing hemodialysis. However, scant studies focused on continuous observations of serum magnesium levels. OBJECTIVE: To provide continuous observations of serum magnesium levels in patients on maintenance hemodialysis (MHD). The levels of magnesium in patients initiating hemodialysis are also recorded and analyzed in the present study. METHODS: In this retrospective study, we serially investigated the measurements of serum total magnesium in MHD patients and patients initiating hemodialysis. Our data were followed up for one year. We provided real-time update on the levels of serum magnesium in patients on hemodialysis. RESULTS: On January 1, 2019, a total of 356 end-stage renal diseasepatients were receiving hemodialysis in our hospital. On December 31, 2019, the number had increased to 383. We found that serum total magnesium levels were in the normal range before initiating hemodialysis. With the initiation of hemodialysis, the levels of serum total magnesium increased. In patients on MHD, hypermagnesemia was very common. Hypomagnesemia was rare when 0.5 mmol/L magnesium dialysate was used. We did not find proton pump inhibitor associated hypomagnesemia. CONCLUSION: We find that serum total magnesium levels are in the normal range before initiating hemodialysis. However, in patients on MHD, hypermagnesemia is common when 0.5 mmol/L magnesium dialysate is used. Hypomagnesemia is very rare. Hypomagnesemia in patients on MHD is an indicator of poor condition.
Authors: Andrea Rosanoff; Christina West; Ronald J Elin; Oliver Micke; Shadi Baniasadi; Mario Barbagallo; Emily Campbell; Fu-Chou Cheng; Rebecca B Costello; Claudia Gamboa-Gomez; Fernando Guerrero-Romero; Nana Gletsu-Miller; Bodo von Ehrlich; Stefano Iotti; Ka Kahe; Dae Jung Kim; Klaus Kisters; Martin Kolisek; Anton Kraus; Jeanette A Maier; Magdalena Maj-Zurawska; Lucia Merolle; Mihai Nechifor; Guitti Pourdowlat; Michael Shechter; Yiqing Song; Yee Ping Teoh; Rhian M Touyz; Taylor C Wallace; Kuninobu Yokota; Federica Wolf Journal: Eur J Nutr Date: 2022-06-10 Impact factor: 4.865