| Literature DB >> 32865107 |
Alexander Bäuerle1, Jasmin Steinbach1, Adam Schweda1, Jil Beckord1, Madeleine Hetkamp1, Benjamin Weismüller1, Hannah Kohler1, Venja Musche1, Nora Dörrie1, Martin Teufel1, Eva-Maria Skoda1.
Abstract
INTRODUCTION: COVID-19 is causing an enormous psychological burden for most people. This study aims to assess individual changes in mental health and health status before and after the COVID-19 outbreak, and to explore potential predictors of change.Entities:
Keywords: COVID-19; anxiety; changes in mental health; depression; mental health; predictors of change
Mesh:
Year: 2020 PMID: 32865107 PMCID: PMC7457643 DOI: 10.1177/2150132720953682
Source DB: PubMed Journal: J Prim Care Community Health ISSN: 2150-1319
Demographic Characteristics.
| n | % | |
|---|---|---|
|
| ||
| Female | 10 633 | 70.7 |
| Male | 4353 | 28.9 |
| Inter/ diverse | 51 | 0.3 |
|
| ||
| 18 to 24 years | 2076 | 13.8 |
| 25 to 34 years | 3725 | 24.8 |
| 35 to 44 years | 3459 | 23.0 |
| 45 to 54 years | 2846 | 18.9 |
| 55 to 64 years | 2151 | 14.3 |
| 65 to 74 years | 662 | 4.4 |
| ≥75 years | 109 | 0.8 |
|
| ||
| Single | 4300 | 28.6 |
| Married | 6391 | 42.5 |
| In a relationship | 3129 | 20.8 |
| Divorced/separated | 922 | 6.1 |
| Widowed | 197 | 1.3 |
| Other | 98 | 0.7 |
|
| ||
| Yes | 4281 | 28.5 |
| No | 10 756 | 71.5 |
|
| ||
| University education | 6403 | 42.6 |
| Higher education entrance qualification | 4921 | 32.7 |
| Secondary education | 2761 | 18.4 |
| Lower secondary education | 655 | 4.4 |
| No qualification | 47 | 0.3 |
| Other | 244 | 1.6 |
|
| ||
| 100 000 residents | 8396 | 55.8 |
| 20 000 residents | 3417 | 22.7 |
| 5000 residents | 1645 | 10.9 |
| <5000 residents | 1579 | 10.5 |
|
| ||
| Not employed | 1544 | 10.3 |
| Health-care related job | 2195 | 14.6 |
| Other | 11 257 | 75.1 |
|
| ||
| Somatic | 3577 | 23.8 |
| Psychiatric | 1976 | 13.1 |
| None | 9484 | 63.1 |
|
|
|
|
Prevalence of Generalized Anxiety Symptoms, Depression Symptoms, and Distress Before and After the COVID-19 Outbreak.
| Before COVID-19 outbreak | After COVID-19 outbreak | |
|---|---|---|
| PHQ-2 | ||
| °<3 | 13 896 (92.4%) | 12 880 (85.7%) |
| °≥3 | 1141 (7.6%) | 2157 (14.3%) |
| GAD-2 | ||
| °<3 | 13 677 (91.0%) | 12 070 (80.3%) |
| °≥3 | 1360 (9.0%) | 2967 (19.7%) |
| DT | ||
| °<4 | 7247 (48.2%) | 5238 (34.8%) |
| °≥4 | 7790 (51.8%) | 9799 (65.2%) |
|
| 15 037 (100.0%) | 15 037 (100.0%) |
Abbreviations: DT: Distress Thermometer, a score of ≥ 4 indicates elevated distress; GAD-2: Generalized Anxiety Disorder Scale-2, sum scores of ≥3 indicate severe generalized anxiety symptoms; PHQ-2: Patient Health Questionnaire-2, sum scores of ≥ 3 indicate major depression symptoms.
Prevalence of Generalized Anxiety Symptoms, Depression Symptoms, and Distress Before and After the COVID-19 Outbreak Stratified by Gender.
| Before COVID-19 outbreak | After COVID-19 outbreak | |||||
|---|---|---|---|---|---|---|
| Female | Male | Inter/Divers | Female | Male | Inter/Divers | |
| PHQ-2 | ||||||
| °<3 | 9762 (91.8%) | 4098 (94.1%) | 36 (70.6%) | 9025 (84.9%) | 3822 (87.8%) | 33 (64.7%) |
| °≥3 | 871 (8.2) | 255 (5.9%) | 15 (29.4%) | 1608 (15.1%) | 531 (12.2%) | 18 (35.3%) |
| GAD-2 | ||||||
| °<3 | 9538 (89.7%) | 4100 (94.2%) | 39 (76.5%) | 8226 (77.4%) | 3804 (87.4%) | 40 (78.4%) |
| °≥3 | 1095 (10.3%) | 253 (5.8%) | 12 (23.5%) | 2407 (22.6%) | 549 (12.6%) | 11 (21.6%) |
| DT | ||||||
| °<4 | 4969 (46.7%) | 2262 (52.0%) | 16 (31.4%) | 3423 (32.2%) | 1797 (41.3%) | 18 (35.3%) |
| °≥4 | 5664 (53.3%) | 2091 (48.0%) | 35 (68.6%) | 7210 (67.8) | 2556 (58.7%) | 33 (64.7%) |
|
| 10633 | 4353 | 51 | 10633 | 4353 | 51 |
Abbreviations: DT: Distress thermometer, a score of ≥ 4 indicates elevated distress; PHQ-2: Patient Health Questionnaire-2, sum scores of ≥ 3 indicate major depression symptoms; GAD-2: Generalized Anxiety Disorder Scale-2, sum scores of ≥3 indicate severe generalized anxiety symptoms;
Prevalence of Generalized Anxiety Symptoms, Depression Symptoms, and Distress Before and After The COVID-19 Outbreak Stratified By Age.
| Before COVID-19 outbreak | After COVID-19 outbreak | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 18 to 24 | 25 to 34 | 35 to 44 | 45 to 54 | 55 to 64 | 64+ | 18 to 24 | 25 to 34 | 35 to 44 | 45 to 54 | 55 to 64 | 64+ | |
| PHQ-2 | ||||||||||||
| °<3 | 1715 (82.6%) | 3443 (92.4%) | 3245 (93.8%) | 2691 (94.6%) | 2049 (95.3%) | 753 (96.5%) | 1529 (73.7%) | 3202 (86.0%) | 3005 (86.9%) | 2520 (88.5%) | 1912 (88.9%) | 712 (91.3%) |
| °≥3 | 361 (17.4%) | 282 (7.6%) | 214 (6.2%) | 155 (5.4%) | 102 (4.7%) | 27 (3.5%) | 547 (26.3%) | 523 (14.0%) | 454 (13.1%) | 326 (11.5%) | 239 (11.1%) | 68 (8.7%) |
| GAD-2 | ||||||||||||
| °<3 | 1695 (81.6%) | 3346 (89.8%) | 3209 (92.8%) | 2650 (93.1%) | 2029 (94.3%) | 748 (95.9%) | 1465 (70.6%) | 2948 (79.1%) | 2783 (80.5%) | 2340 (82.2%) | 1832 (85.2%) | 702 (90.0%) |
| °≥3 | 381 (18.4%) | 379 (10.2%) | 250 (7.2%) | 196 (6.9%) | 122 (5.7%) | 32 (4.1%) | 611 (29.4%) | 777 (20.9%) | 676 (19.5%) | 506 (17.8%) | 319 (14.8%) | 78 (10.0%) |
| DT | ||||||||||||
| <4 | 877 (42.2%) | 1747 (46.9%) | 1512 (43 7%) | 1359 (47.8%) | 1174 (54.6%) | 578 (74.1%) | 676 (32.6%) | 1282 (34.4%) | 1024 (29.6%) | 986 (34.6%) | 831 (38.6%) | 439 (56.3%) |
| ≥4 | 1199 (57.8%) | 1978 (53.1%) | 1947 (56.3%) | 1487 (52.2%) | 977 (45.4%) | 202 (25.9%) | 1400 (67.4%) | 2443 (65.6%) | 2435 (70.4%) | 1860 (65.4%) | 1320 (61.4%) | 341 (43.7%) |
|
| 2076 | 3725 | 3459 | 2846 | 2151 | 780 | 2076 | 3725 | 3459 | 2846 | 2151 | 780 |
Abbreviations: DT: Distress thermometer, a score of ≥ 4 indicates elevated distress; GAD-2: Generalized Anxiety Disorder Scale-2, sum scores of ≥3 indicate severe generalized anxiety symptoms; PHQ-2: Patient Health Questionnaire-2, sum scores of ≥ 3 indicate major depression symptoms.
Figure 1.Alterations in mental health between before and after the COVID-19 outbreak.
Mean values and standard errors (SE) +/−1 as error bars from before (pre) and after (post) the COVID-19 outbreak of PHQ-2 = Patient Health Questionnaire-2, MPHQ-2 pre = 0.91 versus MPHQ-2 post = 1.14 (panel a); GAD-2 = Generalized Anxiety Disorder Scale-2, MGAD-2 pre = 1.06 versus MGAD-2 post = 1.52 (panel b); DT = Distress Thermometer, MDT pre = 3.91 vs. MDT post = 4.94 (panel c); EQ-5D-3L = European Quality of Life 5 Dimensions 3 Level, MEQ-5D-3L pre = 82.32 versus MEQ-5D-3L post = 80.27 (panel d).
Regression Coefficients Predicting an Increase in Depression Symptoms (PHQ-2).
|
|
| t-value | ||
|---|---|---|---|---|
| Intercept | 0.591 | 0.054 | 10.871 | <.001 |
| Mental illness | 0.081 | 0.027 | 2.983 | .003 |
| COVID-19-related fear | 0.046 | 0.005 | 9.074 | <.001 |
| Trust in government | −0.017 | 0.007 | −2.299 | .021 |
| Subjective level of information | −0.088 | 0.010 | −8.802 | <.001 |
Note. Dependent Variable: PHQ-2 (difference between before and after COVID-19 outbreak). Total R² = .014, F(4) = 52.886, P < .001, n = 15 067.
Unstandardized regression coefficients.
Regression Coefficients Predicting an Increase in Generalized Anxiety Symptoms (GAD-2).
|
|
| t-value | ||
|---|---|---|---|---|
| Intercept | 0.348 | 0.062 | 5.630 | <.001 |
| Mental illness | 0.009 | 0.031 | 0.291 | .771 |
| COVID-19-related fear | 0.153 | 0.006 | 26.368 | <.001 |
| Trust in government | −0.038 | 0.008 | −4.702 | <.001 |
| Subjective level of information | −0.072 | 0.011 | −6.342 | <.001 |
Note. Dependent Variable: GAD-2 (difference between before and after COVID-19 outbreak). Total R² = .050, F(4) = 198.394, P < .001, n = 15 067.
Unstandardized regression coefficients.
Regression Coefficients Predicting an Increase in Distress (DT).
|
|
| t-value | ||
|---|---|---|---|---|
| Intercept | 1.548 | 0.116 | 13.363 | <.001 |
| Mental illness | −0.013 | 0.058 | −0.226 | .821 |
| COVID-19-related fear | 0.241 | 0.011 | 22.089 | <.001 |
| Trust in government | −0.096 | 0.015 | −6.257 | <.001 |
| Subjective level of information | −0.204 | 0.021 | −9.631 | <.001 |
Note. Dependent Variable: DT (difference between before and after COVID-19 outbreak). R² = .044, F(4) = 173.495, P < .001, n = 15 067.
Unstandardized regression coefficients.
Regression Coefficients Predicting a Deterioration in Health Status (EQ-5D-3L).
|
|
| t-value | ||
|---|---|---|---|---|
| Intercept | −2.610 | 0.603 | −4.328 | <.001 |
| Mental illness | −1.644 | 0.301 | −5.464 | <.001 |
| COVID-19-related fear | −0.505 | 0.057 | −8.901 | <.001 |
| Trust in government | 0.307 | 0.080 | 3.862 | <.001 |
| Subjective level of information | 0.300 | 0.111 | 2.711 | 0.007 |
Note. Dependent Variable: EQ-5D-3L (difference between before and after COVID-19 outbreak). Total R² = .010, F(10) = 39.939, P < .001, n = 15 067.
Unstandardized regression coefficients.