Xinge Zhang1, Rui Zhang2, Lei Cheng3, Yueqiao Wang4, Xiaoting Ding5, Jialin Fu6, Jiajia Dang7, Justin Moore8, Rui Li9. 1. School of Health Sciences, Wuhan University, Wuhan, 430071, China. Electronic address: bryan@whu.edu.cn. 2. College of Life Sciences, South-Central University for Nationalities, Wuhan, 430074, China. Electronic address: zhangrui@mail.scuec.edu.cn. 3. School of Health Sciences, Wuhan University, Wuhan, 430071, China. Electronic address: chenglei-cherry@whu.edu.cn. 4. Department of Dermatology and Skin Science, University of British Columbia, Vancouver, V5Z 4E8, Canada. Electronic address: elle.wang@ubc.ca. 5. Maternal and Child Health Hospital of Hubei Province, Wuhan, 430071, China. Electronic address: dingxt1991@163.com. 6. School of Health Sciences, Wuhan University, Wuhan, 430071, China. Electronic address: Fjl0708@whu.edu.cn. 7. School of Health Sciences, Wuhan University, Wuhan, 430071, China. Electronic address: jjdang@whu.edu.cn. 8. Department of Family & Community Medicine, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC, 27157, USA; Department of Epidemiology & Prevention, Wake Forest School of Medicine, USA; Department of Implementation Science, Wake Forest School of Medicine, USA. Electronic address: jusmoore@wakehealth.edu. 9. School of Health Sciences, Wuhan University, Wuhan, 430071, China. Electronic address: rli@whu.edu.cn.
Abstract
OBJECTIVE: This systematic review and meta-analysis evaluated the influence of sleep duration or impairment (poor sleep quality, snoring, and obstructive sleep apnea [OSA]) on gestational diabetes mellitus (GDM) risk. METHODS: PubMed, Embase, EBSCO, and WOS databases were searched up to March 4th, 2019. Cohort studies were included and relative risk (RR) with 95% confidence interval (CI) were used as the measure of effects. Heterogeneity was assessed by the Chi-squared and I2 tests. Subgroup analyses, sensitivity analysis, and dose-response analysis were performed. The overall quality of the evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. RESULTS: A total of 16 studies with 2,551,017 pregnant women and 142,103 GDM cases were included in this study. Both short and long sleep duration were associated with increased risk of GDM. There was a U-shaped relationship between sleep duration and GDM risk (P-nonlinearity < 0.001), and pregnant women with 8 h of sleep presented lower GDM risk. Poor sleep quality, snoring and OSA also increased the subsequent risk of GDM. CONCLUSIONS: Pregnant women should be made aware of the benefits of proper sleep, and those with poor sleep quality, snoring, and OSA should be screened for GDM.
OBJECTIVE: This systematic review and meta-analysis evaluated the influence of sleep duration or impairment (poor sleep quality, snoring, and obstructive sleep apnea [OSA]) on gestational diabetes mellitus (GDM) risk. METHODS: PubMed, Embase, EBSCO, and WOS databases were searched up to March 4th, 2019. Cohort studies were included and relative risk (RR) with 95% confidence interval (CI) were used as the measure of effects. Heterogeneity was assessed by the Chi-squared and I2 tests. Subgroup analyses, sensitivity analysis, and dose-response analysis were performed. The overall quality of the evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. RESULTS: A total of 16 studies with 2,551,017 pregnant women and 142,103 GDM cases were included in this study. Both short and long sleep duration were associated with increased risk of GDM. There was a U-shaped relationship between sleep duration and GDM risk (P-nonlinearity < 0.001), and pregnant women with 8 h of sleep presented lower GDM risk. Poor sleep quality, snoring and OSA also increased the subsequent risk of GDM. CONCLUSIONS: Pregnant women should be made aware of the benefits of proper sleep, and those with poor sleep quality, snoring, and OSA should be screened for GDM.
Authors: Qian Yang; Maria Carolina Borges; Eleanor Sanderson; Maria C Magnus; Fanny Kilpi; Paul J Collings; Ana Luiza Soares; Jane West; Per Magnus; John Wright; Siri E Håberg; Kate Tilling; Deborah A Lawlor Journal: PLoS Med Date: 2022-09-06 Impact factor: 11.613
Authors: Eleanor Sanderson; Deborah A Lawlor; Kate Tilling; Maria Carolina Borges; Qian Yang; Maria C Magnus; Fanny Kilpi; Gillian Santorelli; Ana Gonçalves Soares; Jane West; Per Magnus; John Wright; Siri Eldevik Håberg Journal: BMC Med Date: 2022-09-12 Impact factor: 11.150