Emine Turkmen Samdanci1, Ayse Nur Akatli2, Nese Karadag Soylu2. 1. Liver Institute, Pathology Department, Inonu University, School of Medicine, Malatya, Turkey. esamdanci@gmail.com. 2. Liver Institute, Pathology Department, Inonu University, School of Medicine, Malatya, Turkey.
Abstract
PURPOSE: We aimed to distinguish between fibrolamellar hepatocellular carcinoma and scirrhous hepatocellular carcinoma histopathologically. METHODS AND RESULTS: In this review, fibrolamellar hepatocellular carcinoma and scirrhous hepatocellular carcinoma two specific and rare variants of hepatocellular carcinoma, which are difficult to diagnose histopathologically are discussed. CONCLUSION: The clinical, radiological, gross, histopathological, immunohistochemical, and molecular features of these two tumors, which are defined by the World Health Organization (WHO), are mentioned.
PURPOSE: We aimed to distinguish between fibrolamellar hepatocellular carcinoma and scirrhous hepatocellular carcinoma histopathologically. METHODS AND RESULTS: In this review, fibrolamellar hepatocellular carcinoma and scirrhous hepatocellular carcinoma two specific and rare variants of hepatocellular carcinoma, which are difficult to diagnose histopathologically are discussed. CONCLUSION: The clinical, radiological, gross, histopathological, immunohistochemical, and molecular features of these two tumors, which are defined by the World Health Organization (WHO), are mentioned.
Authors: Teodoro Rudolphi-Solero; Eva María Triviño-Ibáñez; Antonio Medina-Benítez; Javier Fernández-Fernández; Daniel José Rivas-Navas; Alejandro José Pérez-Alonso; Manuel Gómez-Río; Tarik Aroui-Luquin; Antonio Rodríguez-Fernández Journal: Diagnostics (Basel) Date: 2021-12-27