Literature DB >> 32856844

Commentary Regarding the Effect of Long Term Use of Finasteride on Saudi Women.

Wedad Saeed Al-Qahtani1, Gadah Albasher2, Saad Alkahtani2.   

Abstract

In the following commentary, we provided discussions regarding an article bublished by Albasher et al. (2020) concerning the effects of long-term use of finasteride on women. They reported some adverse effects, including abnormal levels in the steroid hormones, irregular menstrual cycles, and heavy menstrual bleeding. Some concerns exist in the study mainly concerning the sample, particularly its size and composition. The authors recruited Saudi women. Thus, the findings cannot be generalized. Their study can be seen as a starting point in this regard. Even though the concerns can restrict the study, their study is still credible addressing critical issues that need to be taken seriously by other researchers and stakeholders.

Entities:  

Keywords:  Finasteride; Steroids; Women; menstrual bleeding

Mesh:

Substances:

Year:  2020        PMID: 32856844      PMCID: PMC7771956          DOI: 10.31557/APJCP.2020.21.8.2197

Source DB:  PubMed          Journal:  Asian Pac J Cancer Prev        ISSN: 1513-7368


  7 in total

1.  The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia.

Authors:  L Drake; M Hordinsky; V Fiedler; J Swinehart; W P Unger; P C Cotterill; D M Thiboutot; N Lowe; C Jacobson; D Whiting; S Stieglitz; S J Kraus; E I Griffin; D Weiss; P Carrington; C Gencheff; G W Cole; D M Pariser; E S Epstein; W Tanaka; A Dallob; K Vandormael; L Geissler; J Waldstreicher
Journal:  J Am Acad Dermatol       Date:  1999-10       Impact factor: 11.527

2.  Follicular miniaturization in female pattern hair loss: clinicopathological correlations.

Authors:  A G Messenger; R Sinclair
Journal:  Br J Dermatol       Date:  2006-11       Impact factor: 9.302

3.  Comparison on serum biomarkers for anovulatory and ovulatory dysfunctional uterine bleeding in Lizu females.

Authors:  Shan Bao; Shu-Ying Yang; Zhuo-Ri Li; Ge-Bo Wen
Journal:  Asian Pac J Trop Med       Date:  2014-02       Impact factor: 1.226

Review 4.  Androgenetic alopecia in women.

Authors:  Vera H Price
Journal:  J Investig Dermatol Symp Proc       Date:  2003-06

5.  Genetic and environmental determinants of menstrual characteristics.

Authors:  Shayesteh Jahanfar
Journal:  Indian J Hum Genet       Date:  2012-05

6.  Finasteride 5 mg/day Treatment of Patterned Hair Loss in Normo-androgenetic Postmenopausal Women.

Authors:  R Oliveira-Soares; J Maia E Silva; M Peres Correia; Marisa C André
Journal:  Int J Trichology       Date:  2013-01

7.  Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women.

Authors:  Gadah Albasher; May Bin-Jumah; Saleh Alfarraj; Fatimah Al-Otibi; Nouf K Al-Sultan; Saud Alarifi; Saad Alkahtani; Nahed S Alharthi; Wedad S Al-Qahtani
Journal:  Biosci Rep       Date:  2020-02-28       Impact factor: 3.840

  7 in total

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