BACKGROUND: This report evaluates hospital blood use trends during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, and identifies factors associated with the need for transfusion and risk of death in patients with coronavirus 2019 (COVID-19). METHODS: Overall hospital blood use and medical records of adult patients with COVID-19 were extracted for two institutions. Multivariate logistic regression models were conducted to estimate associations between the outcomes transfusion and mortality and patient factors. RESULTS: Daily blood use decreased compared to pre-COVID-19 levels; the effect was more significant for platelets (29% and 34%) compared to red blood cells (25% and 20%) at the two institutions, respectively. Surgical and oncologic services had a decrease in average daily use of platelets of 52% and 30%, and red blood cells of 39% and 25%, respectively. A total of 128 patients with COVID-19 were hospitalized, and 13 (10%) received at least one transfusion due to anemia secondary to chronic illness (n = 7), recent surgery (n = 3), and extracorporeal membrane oxygenation (n = 3). Lower baseline platelet count and admission to the intensive care unit were associated with increased risk of transfusion. The blood group distribution in patients with COVID-19 was 37% group O, 40% group A, 18% group B, and 5% group AB. Non-type O was not associated with increased risk of mortality. CONCLUSION: The response to the SARS-CoV-2 pandemic included changes in routine hospital operations that allowed for the provision of a sufficient level of care for patients with and without COVID-19. Although blood type may play a role in COVID-19 susceptibility, it did not seem to be associated with patient mortality.
BACKGROUND: This report evaluates hospital blood use trends during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, and identifies factors associated with the need for transfusion and risk of death in patients with coronavirus 2019 (COVID-19). METHODS: Overall hospital blood use and medical records of adult patients with COVID-19 were extracted for two institutions. Multivariate logistic regression models were conducted to estimate associations between the outcomes transfusion and mortality and patient factors. RESULTS: Daily blood use decreased compared to pre-COVID-19 levels; the effect was more significant for platelets (29% and 34%) compared to red blood cells (25% and 20%) at the two institutions, respectively. Surgical and oncologic services had a decrease in average daily use of platelets of 52% and 30%, and red blood cells of 39% and 25%, respectively. A total of 128 patients with COVID-19 were hospitalized, and 13 (10%) received at least one transfusion due to anemia secondary to chronic illness (n = 7), recent surgery (n = 3), and extracorporeal membrane oxygenation (n = 3). Lower baseline platelet count and admission to the intensive care unit were associated with increased risk of transfusion. The blood group distribution in patients with COVID-19 was 37% group O, 40% group A, 18% group B, and 5% group AB. Non-type O was not associated with increased risk of mortality. CONCLUSION: The response to the SARS-CoV-2 pandemic included changes in routine hospital operations that allowed for the provision of a sufficient level of care for patients with and without COVID-19. Although blood type may play a role in COVID-19 susceptibility, it did not seem to be associated with patientmortality.
Authors: Leandro Felipe Figueiredo Dalmazzo; Alyne Ferreira de Almendra Freitas; Brunna Eulálio Alves; Diogo Kloppel Cardoso; Eduardo Ferro de Carvalho; Fabiana Akil; Fernanda da Cunha Vieira Perini; Karina Todeschini Pires; Ludmila Coutinho de Aguiar; Mara Cabral Moraes; Maria Isabel Ayrosa Madeira; Pablo Raphael Gomiero Alves; Ruth Helena Perdiz Watanabe; Silvia Helena da Silva Sá Teixeira; Tatiana Covas Pereira; Viviani de Lourdes Rosa Pessoa; Sérgio Domingos Vieira Journal: Vox Sang Date: 2021-02-26 Impact factor: 2.996
Authors: Arwa Z Al-Riyami; Thierry Burnouf; Erica M Wood; Dana V Devine; Adaeze Oreh; Torunn Oveland Apelseth; Ruchika Goel; Evan M Bloch; Karin van Den Berg; Mahrukh Getshen; Vernon Louw; Ai Leen Ang; Cheuk Kwong Lee; Naomi Rahimi-Levene; Susan L Stramer; Ralph Vassallo; Torsten J Schulze; Gopal Kumar Patidar; Hem Chandra Pandey; Rounak Dubey; Maha Badawi; Salwa Hindawi; Abdullah Meshi; Tadashi Matsushita; Enrico Sorrentino; Rada M Grubovic Rastvorceva; Renée Bazin; Marion Vermeulen; Susan Nahirniak; Hamilton C Tsang; Hans Vrielink; Teguh Triyono; Marcelo Addas-Carvalho; Ana Hećimović; Oscar W Torres; Samclide M Mutindu; Jesper Bengtsson; Diego Dominguez; Ahmed Sayedahmed; Rozi Hanisa Musa; Bipul Gautam; Eszter Herczenik; Cynthia So-Osman Journal: Vox Sang Date: 2022-03-08 Impact factor: 2.996
Authors: Wen Lu; Mark Yazer; Na Li; Alyssa Ziman; Silvano Wendel; Hongying Tang; Hamilton Tsang; Kjell Titlestad; Suzanne R Thibodeaux; Andrew W Shih; Jessica L Poisson; Tho Pham; Suchi Pandey; Monica B Pagano; Hua Shan; Mike Murphy; Colin Murphy; Mariana Lorenzi Savioli; José Mauro Kutner; Aaron S Hess; Magali J Fontaine; Roberta Fachini; Nancy M Dunbar; Richard M Kaufman Journal: Transfusion Date: 2022-07-15 Impact factor: 3.337
Authors: Kevin E Shopsowitz; Christina Lim; Andrew W Shih; Nick Fishbane; Brian R Berry; Mark Bigham; Tanya Petraszko; Jacqueline Trudeau; Maureen Wyatt; Matthew T S Yan; Douglas Morrison Journal: Vox Sang Date: 2021-07-26 Impact factor: 2.996
Authors: Robert A DeSimone; Victoria A Costa; Kathleen Kane; Jorge L Sepulveda; Grant B Ellsworth; Roy M Gulick; Jason Zucker; Magdalena E Sobieszcyk; Joseph Schwartz; Melissa M Cushing Journal: Transfusion Date: 2020-11-20 Impact factor: 3.337