| Literature DB >> 32854499 |
Ju Hu1, Jin Wang1, Qing-Xia Gan1, Qian Ran1, Guan-Hua Lou1, Hai-Jun Xiong1, Cheng-Yi Peng1, Ji-Lin Sun2, Ren-Chuan Yao3, Qin-Wan Huang1.
Abstract
Metabolic diseases constitute a major public health burden and are linked with high morbidity and mortality. They comprise atherosclerosis dyslipidemia, diabetes, hypertension, and obesity. However, there is no single drug that can simultaneously treat multiple diseases with complex underlying mechanisms. Therefore, it is necessary to identify a class of adjuvant drugs that block the development of metabolic diseases from a preventive perspective. Red yeast rice is a food fermentation product widely used to promote blood circulation and remove blood stasis. Modern pharmacology has shown that red yeast rice exerts potential protective effects on the liver, pancreas, blood vessels, and intestines. Therefore, this study was carried out to analyze and summarize the effect of red yeast rice on several metabolic diseases and the mechanisms of action involved. It was found that red yeast rice may be beneficial in the prevention and treatment of metabolic diseases.Entities:
Keywords: metabolic diseases; multiple pathways; multiple targets; red yeast rice
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Year: 2020 PMID: 32854499 DOI: 10.1021/acs.jafc.0c01893
Source DB: PubMed Journal: J Agric Food Chem ISSN: 0021-8561 Impact factor: 5.279