Literature DB >> 32853096

Going Beyond VEGF Pathway Inhibition for Antiangiogenic Cancer Therapy: Is Inhibition of the PP2A/B55α Complex the Answer?

John D Martin1, Dan G Duda2, Rakesh K Jain2.   

Abstract

Entities:  

Keywords:  Editorials; basement membrane; biomarker; disease progression; hypoxia; pericytes

Mesh：

Substances：

Year:  2020        PMID： 32853096      PMCID： PMC7462096          DOI： 10.1161/CIRCRESAHA.120.317720

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


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  16 in total

1.  B55α/PP2A Limits Endothelial Cell Apoptosis During Vascular Remodeling: A Complementary Approach To Disrupt Pathological Vessels?

Authors:  Manuel Ehling; Ward Celus; Rosa Martín-Pérez; Roser Alba-Rovira; Sander Willox; Donatella Ponti; Maria C Cid; Elizabeth A V Jones; Giusy Di Conza; Massimiliano Mazzone
Journal:  Circ Res       Date:  2020-06-12       Impact factor: 17.367

Review 2.  Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges.

Authors:  John D Martin; Giorgio Seano; Rakesh K Jain
Journal:  Annu Rev Physiol       Date:  2019-02-10       Impact factor: 19.318

3.  Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion.

Authors:  A Gregory Sorensen; Kyrre E Emblem; Pavlina Polaskova; Dominique Jennings; Heisoog Kim; Marek Ancukiewicz; Meiyun Wang; Patrick Y Wen; Percy Ivy; Tracy T Batchelor; Rakesh K Jain
Journal:  Cancer Res       Date:  2011-11-29       Impact factor: 12.701

Review 4.  Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges.

Authors:  Dai Fukumura; Jonas Kloepper; Zohreh Amoozgar; Dan G Duda; Rakesh K Jain
Journal:  Nat Rev Clin Oncol       Date:  2018-03-06       Impact factor: 66.675

5.  Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

Authors:  Frank Winkler; Sergey V Kozin; Ricky T Tong; Sung-Suk Chae; Michael F Booth; Igor Garkavtsev; Lei Xu; Daniel J Hicklin; Dai Fukumura; Emmanuelle di Tomaso; Lance L Munn; Rakesh K Jain
Journal:  Cancer Cell       Date:  2004-12       Impact factor: 31.743

6.  Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer.

Authors:  Rebecca S Heist; Dan G Duda; Dushyant V Sahani; Marek Ancukiewicz; Panos Fidias; Lecia V Sequist; Jennifer S Temel; Alice T Shaw; Nathan A Pennell; Joel W Neal; Leena Gandhi; Thomas J Lynch; Jeffrey A Engelman; Rakesh K Jain
Journal:  Proc Natl Acad Sci U S A       Date:  2015-01-20       Impact factor: 11.205

7.  Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies.

Authors:  Chrysovalantis Voutouri; Nathaniel D Kirkpatrick; Euiheon Chung; Fotios Mpekris; James W Baish; Lance L Munn; Dai Fukumura; Triantafyllos Stylianopoulos; Rakesh K Jain
Journal:  Proc Natl Acad Sci U S A       Date:  2019-01-30       Impact factor: 11.205

8.  Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients.

Authors:  Sara M Tolaney; Yves Boucher; Dan G Duda; John D Martin; Giorgio Seano; Marek Ancukiewicz; William T Barry; Shom Goel; Johanna Lahdenrata; Steven J Isakoff; Eren D Yeh; Saloni R Jain; Mehra Golshan; Jane Brock; Matija Snuderl; Eric P Winer; Ian E Krop; Rakesh K Jain
Journal:  Proc Natl Acad Sci U S A       Date:  2015-11-02       Impact factor: 11.205

9.  Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.

Authors:  Tracy T Batchelor; Elizabeth R Gerstner; Kyrre E Emblem; Dan G Duda; Jayashree Kalpathy-Cramer; Matija Snuderl; Marek Ancukiewicz; Pavlina Polaskova; Marco C Pinho; Dominique Jennings; Scott R Plotkin; Andrew S Chi; April F Eichler; Jorg Dietrich; Fred H Hochberg; Christine Lu-Emerson; A John Iafrate; S Percy Ivy; Bruce R Rosen; Jay S Loeffler; Patrick Y Wen; A Greg Sorensen; Rakesh K Jain
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-04       Impact factor: 11.205

10.  Combining two strategies to improve perfusion and drug delivery in solid tumors.

Authors:  Triantafyllos Stylianopoulos; Rakesh K Jain
Journal:  Proc Natl Acad Sci U S A       Date:  2013-10-28       Impact factor: 11.205
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