Literature DB >> 3285206

Sequence and structure of a Plasmodium falciparum telomere.

K D Vernick1, T F McCutchan.   

Abstract

We have isolated a 3 kb cloned DNA fragment which originated from a telomere of the human malaria parasite Plasmodium falciparum. The complete nucleotide sequence of the clone is presented. The clone is composed of several distinct structural regions which vary in their sequence complexity. Using oligonucleotide probes for the different structural regions, we analyzed the genetic conservation of sequence organization near telomeres in various strains of P. falciparum. Our results suggest that rapid sequence variability is generated in the vicinity of chromosome ends.

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Year:  1988        PMID： 3285206     DOI： 10.1016/0166-6851(88)90055-2

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  26 in total

Review 1.  Repetitive elements in genomes of parasitic protozoa.

Authors:  Bill Wickstead; Klaus Ersfeld; Keith Gull
Journal:  Microbiol Mol Biol Rev       Date:  2003-09       Impact factor: 11.056

2.  Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro.

Authors:  B A Biggs; D J Kemp; G V Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

3.  Cloning and characterization of chromosome breakpoints of Plasmodium falciparum: breakage and new telomere formation occurs frequently and randomly in subtelomeric genes.

Authors:  A Scherf; D Mattei
Journal:  Nucleic Acids Res       Date:  1992-04-11       Impact factor: 16.971

4.  Organization of subtelomeric repeats in Plasmodium berghei.

Authors:  E Dore; T Pace; M Ponzi; L Picci; C Frontali
Journal:  Mol Cell Biol       Date:  1990-05       Impact factor: 4.272

5.  Long insertions within telomeres contribute to chromosome size polymorphism in Plasmodium berghei.

Authors:  T Pace; M Ponzi; E Dore; C Janse; B Mons; C Frontali
Journal:  Mol Cell Biol       Date:  1990-12       Impact factor: 4.272

6.  Expression of the RESA gene in Plasmodium falciparum isolate FCR3 is prevented by a subtelomeric deletion.

Authors:  R Cappai; M R van Schravendijk; R F Anders; M G Peterson; L M Thomas; A F Cowman; D J Kemp
Journal:  Mol Cell Biol       Date:  1989-08       Impact factor: 4.272

7.  Detection of all human Plasmodium species by a telomeric DNA fragment cloned from Plasmodium berghei.

Authors:  T Pace; B Mons
Journal:  Bull World Health Organ       Date:  1988       Impact factor: 9.408

8.  The polymorphic subtelomeric regions of Plasmodium falciparum chromosomes contain arrays of repetitive sequence elements.

Authors:  D de Bruin; M Lanzer; J V Ravetch
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-18       Impact factor: 11.205

9.  Characterisation of the telomeres at opposite ends of a 3 Mb Theileria parva chromosome.

Authors:  B K Sohanpal; S P Morzaria; E I Gobright; R P Bishop
Journal:  Nucleic Acids Res       Date:  1995-06-11       Impact factor: 16.971

10.  Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests.

Authors:  Joanne Baker; Mei-Fong Ho; Anita Pelecanos; Michelle Gatton; Nanhua Chen; Salim Abdullah; Audrey Albertini; Frederic Ariey; John Barnwell; David Bell; Jane Cunningham; Djibrine Djalle; Diego F Echeverry; Dionicia Gamboa; Jeffery Hii; Myat Phone Kyaw; Jennifer Luchavez; Christopher Membi; Didier Menard; Claribel Murillo; Sina Nhem; Bernhards Ogutu; Pamela Onyor; Wellington Oyibo; Shan Qing Wang; James McCarthy; Qin Cheng
Journal:  Malar J       Date:  2010-05-17       Impact factor: 2.979
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