Early pregnancy mood before and during COVID-19 community restrictions among women of low socioeconomic status in New York City: a preliminary study.

To explore the mental health consequences of COVID-19-related social restrictions on pregnant women living in low socioeconomic status. Prenatal women appearing at the Mount Sinai Hospital Ambulatory Practice were screened for mood symptomatology from February 2, 2020, through June 12, 2020. An improvement in prenatal mood was observed following social restrictions compared to before the pandemic. The impact of COVID-19 remains largely unknown and may be useful towards understanding the needs of pregnant women living in poverty.

Introduction

Addressing the mental health needs of pregnant women during the Coronavirus disease 2019 (COVID-19) pandemic is an increasing concern among obstetricians and mental health clinicians. According to a recent Kaiser Family Foundation poll (2020), the majority of adults report their lives have been disrupted by the virus (84%), and nearly half (45%) report their mental health has been negatively impacted. While minority women living in low socioeconomic status (SES) are among the most vulnerable for mood disruption during pregnancy (Shakeel et al. 2015), how the COVID-19 pandemic, and accompanying social restrictions, may impact this population remains unknown.

This study, therefore, aimed to explore how social restrictions associated with the COVID-19 pandemic may be impacting prenatal women living in low SES. The results of this exploration will help better understand the needs of women in poverty, both during the pandemic and thereafter.

Methods

In 2011, the Mount Sinai Hospital Obstetrics & Gynecology Ambulatory Practice initiated the first large-scale universal symptomatology screening for perinatal mood utilizing clinical decision support tied into electronic medical records (Loudon et al. 2016). In February of 2020, to further improve clinical services, the assessment of mood at a woman’s first prenatal visit was added.

Sample characteristics

The study cohort consisted of the entire population of women who appeared for their first prenatal appointment at the Mount Sinai Hospital OB/GYN Ambulatory Practice between February 3, 2020, and June 12, 2020. The Ambulatory Practice serves a population of primarily Hispanic and African-American minority women (90%) who reside in the inner city. The remaining 10% of women self-identify as Asian, Caucasian, Filipino, Indian, Islander, Native American, and “unknown.” Approximately 70% of the women reported being single or unmarried at their first preterm appointment, and 90% were enrolled in a US government–funded healthcare plan.

Mood assessment

The Edinburgh Postnatal Depression Scale (EPDS; Cox et al. 1987) was provided to all women as a screen for prenatal mood dysregulation. The EPDS is a ten-item self-report multidimensional instrument, validated in over 36 languages, capable of assessing symptoms associated with depression and anxiety using a scale of 0–30. Initially designed to assess postpartum mood, the EPDS effectively assesses mood throughout pregnancy (Meijer et al. 2014). When used as a first step in screening for significant mood changes or when used in a retrospective study for statistical analysis, the recommended cutoff score of ≥ 9 indicates symptomatology consistent with possible depression, whereas a cutoff score of ≥ 12 indicates probable depression, with a sensitivity of 86%, and a specificity of 78% (Cox et al. 1987). Whenever possible, assessments were provided in the patient’s primary language.

Analysis

The patient’s date of service and EPDS score was downloaded directly from the Mount Sinai Hospital network and imported into SAS 9.2 for analysis. To accomplish the study aims, two separate analyses were run. First, women were divided into groups of those screened before and those after New York’s March 12, 2020, ban on large gatherings, and second, those who appeared and were screened during the 6 weeks before imposing social restrictions (February 2, 2020-March 11, 2020) and those appearing and screened during the last 6 weeks of available data (May 4, 2020–June 12, 2020).

All work was performed in compliance with the Mount Sinai School of Medicine Program for the Protection of Human Subjects and in accordance with the Health Insurance Portability and Accountability Act (HIPAA) security rule guidelines enacted in 2003.

Results

Of the 488 women who appeared for their first prenatal appointment between February 3, 2020, and June 12, 2020, 485 women (ages 16–40 years) had recorded EPDS scores; three women declined EPDS screening. Of the women who completed the EPDS, 406 (83.7%) reported some change of mood over the past 2 weeks (EPDS ≥ 1), 73 women (15.1%) had a score ≥ 9, and 40 women (8.2%) had a score ≥ 12 (mean = 4.7, median = 4, range = 0–22, SD = 4.2). While there was no significant difference observed in mean EPDS scores between women screened before (n = 153; mean = 5.0, median = 4, range = 0–21, SD = 4.4) and following (n = 332; mean = 4.5, median = 4, range = 0–22, SD = 4.0) the March 12, 2020, restrictions, t(483) = 1.16, p = 0.25, n.s., a significant difference in EPDS scores were observed between those women who appeared for their first prenatal appointment in the 6 weeks prior to restrictions (n = 154; mean = 5.0, median = 4, range = 0–21, SD = 4.4) compared with those who appeared the last 6 weeks of available data, May 4, 2020–June 12, 2020 (n = 155; mean = 3.9, median = 3, range = 0–14, SD = 3.6), t(307) = 2.51, p < 0.01; corresponding to restrictions of schools and nonessential business. Notably, this difference is related to decreased symptomatology. (Fig. 1).

Fig. 1

Observed EPDS average by week

Discussion

Women living in low socioeconomic status in New York City demonstrated an improvement in mood in light of the implementation of social restrictions in New York City secondary to the COVID-19 pandemic. While the pandemic’s effects on pregnant women are of considerable concern among clinicians who treat pregnant women, surprisingly, symptoms of mood dysregulation for minority women of low SES appeared to decline.

On March 12, 2020, the World Health Organization declared the outbreak of COVID-19 a global pandemic, and community-wide restrictions closing school and non-essential business were mandated across New York State. Although considerable efforts have focused on the medical challenges associated with COVID-19, less attention has been focused on the mental health implications of the “shut-down” during pregnancy. That we found lower rates of depression symptomatology among minority women is consistent with an increasing body of research demonstrating minority women living in low socioeconomic status may be less likely to suffer from acute episodes of depression (Bailey et al. 2019), may be more resilient to effects of stressful life events (Assari and Lankarani 2016), and may also be more emotionally resilient in the face of opportunistic illness (Dale and Safren 2018). Equally notable is that some consequences of imposed social restrictions may have had unexpected positive effects on health and wellbeing (see Nelson 2020), specifically among those living in lower SES. For example, the well-understood social and economic factors which disproportionately impact mothers living in low SES such as unavailable childcare, limited partner and family support, and reduced time flexibility secondary to formal and informal employment obligations, which undoubtedly play a role in contributing to poorer maternal mental health outcomes (Beeber et al. 2008), may have, in many cases, been ameliorated in light of the imposed social restrictions.

While these findings are important towards understanding the early maternal needs of those living in poverty, we recognize some critical limitations. First, the assessment used, the EPDS, a validated measure of mood change throughout pregnancy, may not be sensitive enough to detect symptoms associated specifically with COVID-19 pandemic concerns. However, the specificity and sensitivity to general symptoms of both anxiety (Matthey, 2008) and mood (Cox et al. 1987) as measured by the EPDS are high. Second, we did not analyze the data using demographic factors as covariates. Because there may be a subgroup of pregnant women disproportionally experiencing mood changes, this will need to be further explored as the days of the pandemic continue, and the sample size increases, thereby allowing for appropriate statistical power to determine such differences. Similarly, given the Mount Sinai Hospital OB/GYN Ambulatory Practice’s prenatal EPDS screening program began shortly before the pandemic was announced, and as we presumably remain in the early stages of the crisis, it is also possible that as the pandemic continues and concerns associated with extended unemployment intensify, anxiety and depression among this population will increase. Finally, a problem universal to all health registry–based studies is that outcome variables may only represent treatment-seeking behavior, as opposed to incidence. That is, we can only assess those women who chose to come for their appointments, and given the increased concern of COVID-19 in medical settings, we realize the most anxious and concerned prenatal women may have chosen not to attend their appointments for fear of contracting the virus. Such an occurrence would result in an underestimation of symptoms and could explain why EPDS scores appeared to improve. To explore this possibility, we conducted a post hoc analysis of prenatal appointment attendance for each week to determine if there was a significant difference after restrictions were implemented. No difference was observed (Fig. 2).

Fig. 2

Observed prenatal appointments per week. No significant difference in prenatal appointments by week (p = 0.59, n.s)

Minority women living in low SES are among the most vulnerable for prenatal mood disruption. However, many of the social and economic disparities among those living in lower SES, which likely also play a contributing role to poorer maternal health outcomes, may have been reduced as a result of imposed social restrictions. That we found a decrease in symptomatology is also consistent with a recent Gallop Panel (2020) reporting that many Americans are experiencing less worry than they had earlier in the pandemic. While these findings have implications for urban health policy, as the pandemic continues, and as economic and employment concerns worsen, our results might prove temporary. Certainly, because we are still in the early stages of the pandemic and as maternal stress, anxiety, and depression may adversely affect the infant’s long-term well-being (Kinsella and Monk 2009), monitoring pregnant women for emotional dysregulation continues to warrant special attention.