Ju-Hong Pei1, Xing-Lei Wang2, Yang Yu3, Ya-Bin Zhang1, Lin Gou1, Rui-Ling Nan4, Hai-Xia Chen1, Xin-Man Dou5, Zhi-Jian Han6. 1. School of Nursing, Lanzhou university, Lanzhou, Gansu, People's Republic of China. 2. School of Nursing, Lanzhou university, Lanzhou, Gansu, People's Republic of China; Department of liver diseases branch, Lanzhou University Second Hospital, Lanzhou, Gansu, People's Republic of China. 3. Department of Tumor Surgery, Lanzhou University Second Hospital, Lanzhou, Gansu, People's Republic of China. 4. School of Nursing, Lanzhou university, Lanzhou, Gansu, People's Republic of China; Department of EICU, Lanzhou University Second Hospital, Lanzhou, Gansu, People's Republic of China. 5. School of Nursing, Lanzhou university, Lanzhou, Gansu, People's Republic of China; Department of Nursing, Lanzhou University Second Hospital, Lanzhou, Gansu, People's Republic of China. Electronic address: douxm@lzu.edu.cn. 6. Key Laboratory of the Digestive System Tumors of Gansu Province, Lanzhou University Second Hospital, Lanzhou, Gansu, People's Republic of China. Electronic address: ery_hanzhj@lzu.edu.cn.
Abstract
BACKGROUND: Suicidality is common in patients with migraine. Here, we performed a systematic review and estimated the prevalence of suicidal ideation (SI) and suicide attempt (SA) in patients with migraine. METHODS: We searched Pubmed, Embase, Web of Science, Cochrane database library, CINAHL, and PsycINFO for relevant publications. A random-effects model was used to pool the estimates of the prevalence of SI and SA, which were also stratified by the geographical location of the research institutions from the studies included in this meta-analysis. RESULTS: Fifteen studies involving 2,247,648 participants with migraine were selected. Pooled prevalence estimates of SI and SA were 15.5% [95% confidence interval (CI) 10.4-21.3%] and 3.9% (95% CI 0.9-8.8%), respectively, and the prevalence of SI was higher in Asian countries (21.5%, 95%CI 16.8-26.6%) compared with non-Asian countries (11.0%, 95%CI 6.1-17.2%). Measures of heterogeneity between studies were high for all outcomes (I2 = 89-100%), indicating that the substantial between-study heterogeneity in estimated proportions was not attributed to sampling error. The leave-one-out analysis showed that no single study significantly affected the final pooled results. CONCLUSIONS: This meta-analysis indicated a high prevalence of SI and SA in migraine patients. Thus, it is necessary to design targeted preventive measures for the management of migraine-related suicide.
BACKGROUND: Suicidality is common in patients with migraine. Here, we performed a systematic review and estimated the prevalence of suicidal ideation (SI) and suicide attempt (SA) in patients with migraine. METHODS: We searched Pubmed, Embase, Web of Science, Cochrane database library, CINAHL, and PsycINFO for relevant publications. A random-effects model was used to pool the estimates of the prevalence of SI and SA, which were also stratified by the geographical location of the research institutions from the studies included in this meta-analysis. RESULTS: Fifteen studies involving 2,247,648 participants with migraine were selected. Pooled prevalence estimates of SI and SA were 15.5% [95% confidence interval (CI) 10.4-21.3%] and 3.9% (95% CI 0.9-8.8%), respectively, and the prevalence of SI was higher in Asian countries (21.5%, 95%CI 16.8-26.6%) compared with non-Asian countries (11.0%, 95%CI 6.1-17.2%). Measures of heterogeneity between studies were high for all outcomes (I2 = 89-100%), indicating that the substantial between-study heterogeneity in estimated proportions was not attributed to sampling error. The leave-one-out analysis showed that no single study significantly affected the final pooled results. CONCLUSIONS: This meta-analysis indicated a high prevalence of SI and SA in migrainepatients. Thus, it is necessary to design targeted preventive measures for the management of migraine-related suicide.
Authors: Arão Belitardo de Oliveira; Juliane Prieto Peres Mercante; Isabela M Benseñor; Alessandra C Goulart; Mario Fernando Prieto Peres Journal: Neurol Sci Date: 2021-09-24 Impact factor: 3.307
Authors: Brian B Koo; Ahmed Bayoumi; Abdalla Albanna; Mohammed Abusuliman; Laura Burrone; Jason J Sico; Emmanuelle A D Schindler Journal: J Headache Pain Date: 2021-04-20 Impact factor: 7.277
Authors: Nathan Risch; Jonathan Dubois; Katia M'bailara; Irena Cussac; Bruno Etain; Raoul Belzeaux; Caroline Dubertret; Emmanuel Haffen; Raymund Schwan; Ludovic Samalin; Paul Roux; Mircea Polosan; Marion Leboyer; Philippe Courtet; Emilie Olié Journal: J Clin Med Date: 2022-02-08 Impact factor: 4.241
Authors: X Michelle Androulakis; Siyuan Guo; Jiajia Zhang; Jason Sico; Peter Warren; Alec Giakas; Xiaoming Li; B Lee Peterlin; Roy Mathew; Deborah Reyes Journal: J Pain Res Date: 2021-08-24 Impact factor: 3.133
Authors: Elena P Calandre; Juan M García-Leiva; Jorge L Ordoñez-Carrasco Journal: Int J Environ Res Public Health Date: 2022-07-23 Impact factor: 4.614