Literature DB >> 32840331

Economic burden of Alzheimer disease and managed care considerations.

Winston Wong1.   

Abstract

Alzheimer disease is the most common cause of dementia and the fifth leading cause of death in adults older than 65 years. The estimated total healthcare costs for the treatment of Alzheimer disease in 2020 is estimated at $305 billion, with the cost expected to increase to more than $1 trillion as the population ages. Most of the direct costs of care for Alzheimer disease are attributed to skilled nursing care, home healthcare, and hospice care. Indirect costs of care, including quality of life and informal caregiving, are likely underestimated and are associated with significant negative societal and personal burden. Managed care organizations are in a unique position to develop utilization strategies that would positively impact early diagnosis and treatment to lead to better outcomes and lower costs for patients, caregivers, and the healthcare system. Additionally, the recent inclusion of Alzheimer disease diagnoses into risk corridor calculations by the Centers for Medicare & Medicaid Services may encourage Medicare Advantage organizations to invest in programs that aid in its early detection and diagnosis.

Entities:  

Year:  2020        PMID: 32840331     DOI: 10.37765/ajmc.2020.88482

Source DB:  PubMed          Journal:  Am J Manag Care        ISSN: 1088-0224            Impact factor:   2.229


  42 in total

Review 1.  Deregulated mitochondrial microRNAs in Alzheimer's disease: Focus on synapse and mitochondria.

Authors:  Prashanth Gowda; P Hemachandra Reddy; Subodh Kumar
Journal:  Ageing Res Rev       Date:  2021-11-20       Impact factor: 10.895

2.  Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation.

Authors:  Sivaprakasam R Saroja; Kirill Gorbachev; Tcw Julia; Alison M Goate; Ana C Pereira
Journal:  Proc Natl Acad Sci U S A       Date:  2022-08-15       Impact factor: 12.779

Review 3.  APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases.

Authors:  Rosalía Fernández-Calle; Sabine C Konings; Javier Frontiñán-Rubio; Juan García-Revilla; Lluís Camprubí-Ferrer; Martina Svensson; Isak Martinson; Antonio Boza-Serrano; José Luís Venero; Henrietta M Nielsen; Gunnar K Gouras; Tomas Deierborg
Journal:  Mol Neurodegener       Date:  2022-09-24       Impact factor: 18.879

4.  Emergency and post-emergency care of older adults with Alzheimer's disease/Alzheimer's disease related dementias.

Authors:  Jacob D Hill; Abigail M Schmucker; Nina Siman; Keith S Goldfeld; Allison M Cuthel; Joshua Chodosh; Jean-Baptiste Bouillon-Minois; Corita R Grudzen
Journal:  J Am Geriatr Soc       Date:  2022-05-25       Impact factor: 7.538

Review 5.  The Kappa Opioid Receptor: A Promising Therapeutic Target for Multiple Pathologies.

Authors:  Martin L Dalefield; Brittany Scouller; Rabia Bibi; Bronwyn M Kivell
Journal:  Front Pharmacol       Date:  2022-06-20       Impact factor: 5.988

Review 6.  The hidden link between circadian entropy and mental health disorders.

Authors:  Amal Alachkar; Justine Lee; Kalyani Asthana; Roudabeh Vakil Monfared; Jiaqi Chen; Sammy Alhassen; Muntaha Samad; Marcelo Wood; Emeran A Mayer; Pierre Baldi
Journal:  Transl Psychiatry       Date:  2022-07-14       Impact factor: 7.989

Review 7.  Traditional Chinese Medicine as a Promising Strategy for the Treatment of Alzheimer's Disease Complicated With Osteoporosis.

Authors:  Weifan Xu; Yiping Jiang; Nani Wang; Huanhuan Bai; Shengyan Xu; Tianshuang Xia; Hailiang Xin
Journal:  Front Pharmacol       Date:  2022-06-01       Impact factor: 5.988

Review 8.  Myeloid cells in retinal and brain degeneration.

Authors:  Michelle Guo; Turner D Schwartz; Joshua L Dunaief; Qi N Cui
Journal:  FEBS J       Date:  2021-09-15       Impact factor: 5.622

Review 9.  Alzheimer's Disease: Epidemiology and Clinical Progression.

Authors:  Amir Abbas Tahami Monfared; Michael J Byrnes; Leigh Ann White; Quanwu Zhang
Journal:  Neurol Ther       Date:  2022-03-14

10.  Rational Design of a Cu Chelator That Mitigates Cu-Induced ROS Production by Amyloid Beta.

Authors:  Suchitra Mitra; Kallol Talukdar; Pallavi Prasad; Sandeep K Misra; Shabana Khan; Joshua S Sharp; Jonah W Jurss; Saumen Chakraborty
Journal:  Chembiochem       Date:  2021-12-30       Impact factor: 3.461

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