Literature DB >> 32839194

What Does Uromodulin Do?

Anne Kipp1, Eric Olinger2,3.   

Abstract

Entities:  

Keywords:  blood pressure; cell & transport physiology; chronic kidney disease; distal tubule; genetic renal disease; uromodulin; water-electrolyte balance

Mesh:

Substances:

Year:  2020        PMID: 32839194      PMCID: PMC7792635          DOI: 10.2215/CJN.06390420

Source DB:  PubMed          Journal:  Clin J Am Soc Nephrol        ISSN: 1555-9041            Impact factor:   8.237


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  11 in total

Review 1.  Tubular cross talk in acute kidney injury: a story of sense and sensibility.

Authors:  Tarek M El-Achkar; Pierre C Dagher
Journal:  Am J Physiol Renal Physiol       Date:  2015-04-15

2.  Architecture and function of human uromodulin filaments in urinary tract infections.

Authors:  Gregor L Weiss; Jessica J Stanisich; Maximilian M Sauer; Chia-Wei Lin; Jonathan Eras; Dawid S Zyla; Johannes Trück; Olivier Devuyst; Markus Aebi; Martin Pilhofer; Rudi Glockshuber
Journal:  Science       Date:  2020-07-02       Impact factor: 47.728

3.  Urinary Uromodulin and Risk of Urinary Tract Infections: The Cardiovascular Health Study.

Authors:  Pranav S Garimella; Traci M Bartz; Joachim H Ix; Michel Chonchol; Michael G Shlipak; Prasad Devarajan; Michael R Bennett; Mark J Sarnak
Journal:  Am J Kidney Dis       Date:  2016-10-28       Impact factor: 8.860

4.  Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.

Authors:  Sandosh Padmanabhan; Olle Melander; Toby Johnson; Anna Maria Di Blasio; Wai K Lee; Davide Gentilini; Claire E Hastie; Cristina Menni; Maria Cristina Monti; Christian Delles; Stewart Laing; Barbara Corso; Gerjan Navis; Arjan J Kwakernaak; Pim van der Harst; Murielle Bochud; Marc Maillard; Michel Burnier; Thomas Hedner; Sverre Kjeldsen; Björn Wahlstrand; Marketa Sjögren; Cristiano Fava; Martina Montagnana; Elisa Danese; Ole Torffvit; Bo Hedblad; Harold Snieder; John M C Connell; Morris Brown; Nilesh J Samani; Martin Farrall; Giancarlo Cesana; Giuseppe Mancia; Stefano Signorini; Guido Grassi; Susana Eyheramendy; H Erich Wichmann; Maris Laan; David P Strachan; Peter Sever; Denis Colm Shields; Alice Stanton; Peter Vollenweider; Alexander Teumer; Henry Völzke; Rainer Rettig; Christopher Newton-Cheh; Pankaj Arora; Feng Zhang; Nicole Soranzo; Timothy D Spector; Gavin Lucas; Sekar Kathiresan; David S Siscovick; Jian'an Luan; Ruth J F Loos; Nicholas J Wareham; Brenda W Penninx; Ilja M Nolte; Martin McBride; William H Miller; Stuart A Nicklin; Andrew H Baker; Delyth Graham; Robert A McDonald; Jill P Pell; Naveed Sattar; Paul Welsh; Patricia Munroe; Mark J Caulfield; Alberto Zanchetti; Anna F Dominiczak
Journal:  PLoS Genet       Date:  2010-10-28       Impact factor: 5.917

5.  Multiple loci associated with indices of renal function and chronic kidney disease.

Authors:  Anna Köttgen; Nicole L Glazer; Abbas Dehghan; Shih-Jen Hwang; Ronit Katz; Man Li; Qiong Yang; Vilmundur Gudnason; Lenore J Launer; Tamara B Harris; Albert V Smith; Dan E Arking; Brad C Astor; Eric Boerwinkle; Georg B Ehret; Ingo Ruczinski; Robert B Scharpf; Yii-Der Ida Chen; Ian H de Boer; Talin Haritunians; Thomas Lumley; Mark Sarnak; David Siscovick; Emelia J Benjamin; Daniel Levy; Ashish Upadhyay; Yurii S Aulchenko; Albert Hofman; Fernando Rivadeneira; André G Uitterlinden; Cornelia M van Duijn; Daniel I Chasman; Guillaume Paré; Paul M Ridker; W H Linda Kao; Jacqueline C Witteman; Josef Coresh; Michael G Shlipak; Caroline S Fox
Journal:  Nat Genet       Date:  2009-05-10       Impact factor: 38.330

6.  Uromodulin is expressed in the distal convoluted tubule, where it is critical for regulation of the sodium chloride cotransporter NCC.

Authors:  Natsuko Tokonami; Tomoaki Takata; Jan Beyeler; Iris Ehrbar; Ayumi Yoshifuji; Erik I Christensen; Johannes Loffing; Olivier Devuyst; Eric G Olinger
Journal:  Kidney Int       Date:  2018-07-12       Impact factor: 10.612

7.  Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel.

Authors:  Kaice A LaFavers; Etienne Macedo; Pranav S Garimella; Camila Lima; Shehnaz Khan; Jered Myslinski; Jeanette McClintick; Frank A Witzmann; Seth Winfree; Carrie L Phillips; Takashi Hato; Pierre C Dagher; Xue-Ru Wu; Tarek M El-Achkar; Radmila Micanovic
Journal:  Sci Transl Med       Date:  2019-10-02       Impact factor: 17.956

8.  The Uromodulin Gene Locus Shows Evidence of Pathogen Adaptation through Human Evolution.

Authors:  Silvia Ghirotto; Francesca Tassi; Guido Barbujani; Linda Pattini; Caroline Hayward; Peter Vollenweider; Murielle Bochud; Luca Rampoldi; Olivier Devuyst
Journal:  J Am Soc Nephrol       Date:  2016-03-10       Impact factor: 10.121

9.  Serum uromodulin-a marker of kidney function and renal parenchymal integrity.

Authors:  Jürgen E Scherberich; Rudolf Gruber; Wolfgang Andreas Nockher; Erik Ilsø Christensen; Hans Schmitt; Victor Herbst; Matthias Block; Jürgen Kaden; Wolfgang Schlumberger
Journal:  Nephrol Dial Transplant       Date:  2018-02-01       Impact factor: 5.992

10.  Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression.

Authors:  Olivier Devuyst; Luca Rampoldi; Matteo Trudu; Sylvie Janas; Chiara Lanzani; Huguette Debaix; Céline Schaeffer; Masami Ikehata; Lorena Citterio; Sylvie Demaretz; Francesco Trevisani; Giuseppe Ristagno; Bob Glaudemans; Kamel Laghmani; Giacomo Dell'Antonio; Johannes Loffing; Maria P Rastaldi; Paolo Manunta
Journal:  Nat Med       Date:  2013-11-03       Impact factor: 53.440

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  3 in total

1.  Renal cell markers: lighthouses for managing renal diseases.

Authors:  Shivangi Agarwal; Yashwanth R Sudhini; Onur K Polat; Jochen Reiser; Mehmet M Altintas
Journal:  Am J Physiol Renal Physiol       Date:  2021-10-11

2.  Salt loading decreases urinary excretion and increases intracellular accumulation of uromodulin in stroke-prone spontaneously hypertensive rats.

Authors:  Sheon Mary; Philipp Boder; Giacomo Rossitto; Lesley Graham; Kayley Scott; Arun Flynn; David Kipgen; Delyth Graham; Christian Delles
Journal:  Clin Sci (Lond)       Date:  2021-12-22       Impact factor: 6.124

Review 3.  Current Knowledge of Selected Cardiovascular Biomarkers in Pediatrics: Kidney Injury Molecule-1, Salusin-α and -β, Uromodulin, and Adropin.

Authors:  Mirjam Močnik; Nataša Marčun Varda
Journal:  Children (Basel)       Date:  2022-01-13
  3 in total

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