Literature DB >> 328384

Presence and production of migration inhibitory activity in the peritoneal cavity.

A C Van Maarsseveen.   

Abstract

The presence of migration inhibitory (MI) activity was investigated in the delayed hypersensitivity (DH) reaction induced by i.p. injection of PPD into FCA-sensitized guinea-pigs. Peritoneal exudates were studied at several times before and after the induction of the DH reaction and a non-immune control inflammation. Lymphokine (LK) fractions were prepared from individual exudates and tested in a conventional macrophage migration inhibition assay at concentrations determined to occur in vivo. The results suggest a continuous local production of MI activity and an augmented production during development of a DH reaction.

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Year:  1977        PMID: 328384      PMCID: PMC1445459     

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  9 in total

1.  Lymphokine activity in vivo in relation to circulating monocyte levels and delayed skin reactivity.

Authors:  T Yoshida; S Cohen
Journal:  J Immunol       Date:  1974-04       Impact factor: 5.422

2.  Activity of migration inhibitory factor in the absence of antigen.

Authors:  T Yoshida; C A Janeway; W E Paul
Journal:  J Immunol       Date:  1972-08       Impact factor: 5.422

3.  Role of lymphocyte activation products (LAP) in cell-mediated immunity. I. Preparation and partial purification of guinea-pig LAP.

Authors:  D C Dumonde; D A Page; M Matthew; R A Wolstencroft
Journal:  Clin Exp Immunol       Date:  1972-01       Impact factor: 4.330

4.  The mechanism of action of soluble lymphocytic mediators. I. A pulse exposure test for the measurement of macrophage migration inhibitory factor.

Authors:  S Manheimer; E Pick
Journal:  Immunology       Date:  1973-06       Impact factor: 7.397

5.  'Lymphokines': molecular mediators of cellular immune responses in animals and man.

Authors:  D C Dumonde
Journal:  Proc R Soc Med       Date:  1970-09

6.  Studies on migration inhibitory factor (MIF): recovery of MIF activity after purification by gel filtration and disc electrophoresis.

Authors:  H G Remold; A B Katz; E Haber; J R David
Journal:  Cell Immunol       Date:  1970-05       Impact factor: 4.868

7.  Studies on delayed hypersensitivity pleural exudates in guinea pigs. I. Demonstration of substances in the cell-free exudate which cause inhibition of mononuclear cell migration in vitro.

Authors:  S Yamamoto; C J Dunn; D A Willoughby
Journal:  Immunology       Date:  1976-04       Impact factor: 7.397

8.  The peritoneal exudate lymphocyte. I. Differences in antigen responsiveness between peritoneal exudate and lymph node lymphocytes from immunized guinea pigs.

Authors:  D L Rosenstreich; J T Blake; A S Rosenthal
Journal:  J Exp Med       Date:  1971-11-01       Impact factor: 14.307

9.  Mechanism of action of migration inhibitory factor (MIF). I. Evidence for a receptor for MIF present on the peritoneal macrophage but not on the alveolar macrophage.

Authors:  R W Leu; A L Eddleston; J W Hadden; R A Good
Journal:  J Exp Med       Date:  1972-09-01       Impact factor: 14.307

  9 in total

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