Literature DB >> 3283664

DNA synthesis in gametocytes of Plasmodium falciparum.

C J Janse1, T Ponnudurai, A H Lensen, J H Meuwissen, J Ramesar, M Van der Ploeg, J P Overdulve.   

Abstract

The DNA content of Plasmodium falciparum gametocytes during intra-erythrocytic development and during gametogenesis was established by cytophotometric methods. Intraerythrocytic micro- and macrogametocytes (Stage I-Stage VB) contain about twice the amount of DNA of haploid sporozoites and ringstages, indicating that DNA is synthesized during transformation of ringforms into Stage I gametocytes. Microgametocytes, after activation at pH 8, rapidly duplicate their genome several times, while the DNA content of macrogametocytes remains constant during gametogenesis.

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Year:  1988        PMID： 3283664     DOI： 10.1017/s0031182000081609

Source DB:  PubMed          Journal:  Parasitology        ISSN： 0031-1820            Impact factor:   3.234


  11 in total

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