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Literature DB >> 32833130

Pluripotent Stem Cell Differentiation Toward Functional Basal Stratified Epithelial Cells.

Abstract

In this chapter, an efficient feeder-free protocol of differentiating human pluripotent stem cells (hPSCs) toward the epidermal lineage to generate induced epidermal keratinocytes (iKCs) is described. The iKCs are able to terminally differentiate supra-basally. This hPSC-to-iKC differentiation can serve as a useful model to study epidermal development and disease as well as for therapeutic applications.

Entities: Chemical

Keywords: BMP-4; Differentiation; Keratinocytes; Retinoic acid; Single cell passaging; hPSCs

Mesh：

Year: 2022 PMID： 32833130 DOI： 10.1007/7651_2020_301

Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745

9 in total

1. Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage.

Authors: Ganna Bilousova; Jiang Chen; Dennis R Roop
Journal: J Invest Dermatol Date: 2010-12-09 Impact factor: 8.551

2. Commitment of embryonic stem cells to an epidermal cell fate and differentiation in vitro.

Authors: Tammy-Claire Troy; Kursad Turksen
Journal: Dev Dyn Date: 2005-02 Impact factor: 3.780

3. APR-246/PRIMA-1(MET) rescues epidermal differentiation in skin keratinocytes derived from EEC syndrome patients with p63 mutations.

Authors: Jinfeng Shen; Ellen H van den Bogaard; Evelyn N Kouwenhoven; Vladimir J N Bykov; Tuula Rinne; Qiang Zhang; Geuranne S Tjabringa; Christian Gilissen; Simon J van Heeringen; Joost Schalkwijk; Hans van Bokhoven; Klas G Wiman; Huiqing Zhou
Journal: Proc Natl Acad Sci U S A Date: 2013-01-25 Impact factor: 11.205

4. Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET.

Authors: Ruby Shalom-Feuerstein; Laura Serror; Edith Aberdam; Franz-Josef Müller; Hans van Bokhoven; Klas G Wiman; Huiqing Zhou; Daniel Aberdam; Isabelle Petit
Journal: Proc Natl Acad Sci U S A Date: 2013-01-25 Impact factor: 11.205

5. Reconstituted skin from murine embryonic stem cells.

Authors: Christelle Coraux; Caroline Hilmi; Matthieu Rouleau; Anne Spadafora; Jocelyne Hinnrasky; Jean-Paul Ortonne; Christian Dani; Daniel Aberdam
Journal: Curr Biol Date: 2003-05-13 Impact factor: 10.834

6. Differentiation of human induced pluripotent stem cells into a keratinocyte lineage.

Authors: Igor Kogut; Dennis R Roop; Ganna Bilousova
Journal: Methods Mol Biol Date: 2014

7. TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.

Authors: Lingjie Li; Yong Wang; Jessica L Torkelson; Gautam Shankar; Jillian M Pattison; Hanson H Zhen; Fengqin Fang; Zhana Duren; Jingxue Xin; Sadhana Gaddam; Sandra P Melo; Samantha N Piekos; Jiang Li; Eric J Liaw; Lang Chen; Rui Li; Marius Wernig; Wing H Wong; Howard Y Chang; Anthony E Oro
Journal: Cell Stem Cell Date: 2019-01-24 Impact factor: 24.633

Review 8. A decade of transcription factor-mediated reprogramming to pluripotency.

Authors: Kazutoshi Takahashi; Shinya Yamanaka
Journal: Nat Rev Mol Cell Biol Date: 2016-02-17 Impact factor: 94.444

9. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment.

Authors: Jillian M Pattison; Sandra P Melo; Samantha N Piekos; Jessica L Torkelson; Elizaveta Bashkirova; Maxwell R Mumbach; Charlotte Rajasingh; Hanson Hui Zhen; Lingjie Li; Eric Liaw; Daniel Alber; Adam J Rubin; Gautam Shankar; Xiaomin Bao; Howard Y Chang; Paul A Khavari; Anthony E Oro
Journal: Nat Genet Date: 2018-11-05 Impact factor: 38.330

9 in total

1 in total

Review 1. CRISPR-Cas9‒Based Genomic Engineering in Keratinocytes: From Technology to Application.

Authors: Jos P H Smits; Luca D Meesters; Berber G W Maste; Huiqing Zhou; Patrick L J M Zeeuwen; Ellen H van den Bogaard
Journal: JID Innov Date: 2021-12-01

1 in total