Literature DB >> 32823439

Surgical handling of uveitic membranes in pediatric phakic eyes.

D S Srushti1, Sasikala Elizabeth Anilkumar1, Anuradha Vadakke Kanakath2, Kalpana Narendran1.   

Abstract

Entities:  

Keywords:  Lens sparing procedure; membranectomy; pediatric uveitis; uveitic membrane

Mesh:

Year:  2020        PMID: 32823439      PMCID: PMC7690517          DOI: 10.4103/ijo.IJO_2357_19

Source DB:  PubMed          Journal:  Indian J Ophthalmol        ISSN: 0301-4738            Impact factor:   1.848


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Five- and three-year-old girls with similar presentation of right eye (RE) non-granulomatous anterior uveitis and secondary glaucoma were under steroid, anti-glaucoma medication and post-surgical Peripheral Iridectomy (PI) done 2 weeks back. Visual acuity of RE in case-1 was 20/120 and in case-2 was 20/1000. Anterior segment showed uveitic pupillary membrane with suspected complicated cataract [Figs. 1a and 2a]. In view of visual rehabilitation of the young children, with biometry ready, RE synechiolysis/membranectomy ± cataract extraction with intraocular lens (IOL) implantation was planned. Under adequate viscoelastic, posterior synechiolysis was done. A clear lens underlying a dense fibrotic uveitic membrane was revealed [Figs. 1b and 2b]. By using Utthrata's forceps, the edge of the membrane was secured and peeled out in-toto to expose an undamaged clear lens [Figs. 1c and 2c].
Figure 1

Clinical photograph of the right eye of Case 1: (a) preoperative clinical picture (surgical PI – at 11 o'clock position - occluded) (b) intraoperative picture after synechiolysis showing membrane over lens (c) intraoperative picture during uveitic membrane removal revealing clear lens (d) postoperative clinical picture (a, b and c: surgeon view)

Figure 2

Clinical photograph of the right eye of Case 2: (a) preoperative clinical picture (surgical PI –at 8 o'clock position- patent), (b) intraoperative picture after synechiolysis showing membrane over lens, (c) intraoperative picture during uveitic membrane removal revealing clear lens, and (d) postoperative clinical picture (a, b and c: surgeon view)

Clinical photograph of the right eye of Case 1: (a) preoperative clinical picture (surgical PI – at 11 o'clock position - occluded) (b) intraoperative picture after synechiolysis showing membrane over lens (c) intraoperative picture during uveitic membrane removal revealing clear lens (d) postoperative clinical picture (a, b and c: surgeon view) Clinical photograph of the right eye of Case 2: (a) preoperative clinical picture (surgical PI –at 8 o'clock position- patent), (b) intraoperative picture after synechiolysis showing membrane over lens, (c) intraoperative picture during uveitic membrane removal revealing clear lens, and (d) postoperative clinical picture (a, b and c: surgeon view) Postoperatively RE vision improved to 20/30 in case-1 and 20/240 in case-2. Both children had quiet eyes, visual axis clear, and IOP well controlled [Figs. 1d and 2d].

Discussion

In pediatric uveitis, cataract and pupillary membranes are possible causes of stimulus deprivational amblyopia.[1] Although cataract surgery with IOL has become a relatively safe procedure in pediatric uveitis,[2] case selection is vital. Pupillary membrane can be resolved with lesser complications than cataract surgery. When pupillary membranectomy is planned, it is important to keep in mind that the underlying lens may be clear or have minimal cataract. Apart from Varner,[3] Chan et al.[4] and Rosenberg et al.[5] literature describing the occurrence of pupillary inflammatory membrane as a separate entity, mimicking cataract and surgical handling of such a non-resolving thick fibrotic uveitic membrane and technique of its removal with an underlying clear lens in pediatric uveitis was found lacking. Our article attempts to highlight the importance of lens sparing surgery. Preoperative imaging and biometry are recommendable in such situation. However, all possible measures should be taken to preserve the underlying clear lens during membranectomy.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.
  4 in total

1.  Bilateral, simultaneous, uveitis-associated pupillary membranes.

Authors:  Paul Varner
Journal:  Clin Exp Optom       Date:  2011-04-11       Impact factor: 2.742

2.  Ocular complications of pediatric uveitis.

Authors:  Krista D Rosenberg; William J Feuer; Janet L Davis
Journal:  Ophthalmology       Date:  2004-12       Impact factor: 12.079

3.  Primary intraocular lens implantation in pediatric uveitis: a comparison of 2 populations.

Authors:  Arie Y Nemet; Judith Raz; Dan Sachs; Ronit Friling; Ron Neuman; Michal Kramer; Suresh K Pandi; Vidushi Sharma; Ehud I Assia
Journal:  Arch Ophthalmol       Date:  2007-03

Review 4.  Decision-making and management of uveitic cataract.

Authors:  Nicole Shu-Wen Chan; Seng-Ei Ti; Soon-Phaik Chee
Journal:  Indian J Ophthalmol       Date:  2017-12       Impact factor: 1.848

  4 in total

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