| Literature DB >> 32823142 |
Abstract
Deaths from cholera in Soho, London (late July to end of September 1854) exposed the epidemiology of the disease and demonstrated applied geospatial analysis by highlighting the shortest path principle followed by local residents when they obtained drinking water from a contaminated pump. The present investigation explores if households and individuals with different demographic and socio-economic characteristics were more or less likely to obtain their water from the pump and succumb to the disease. It combines information from the 1851 Population Census and topographic databases with the digital deaths and water pump data to reveal the risk of exposure and the mortality rate were greater for certain occupations, age groups and people living at high residential density irrespective of proximity to the contaminated water pump.Entities:
Keywords: Cholera; Historical GIS; Kernel density estimation; Spatial analysis
Year: 2020 PMID: 32823142 PMCID: PMC7431402 DOI: 10.1016/j.healthplace.2020.102402
Source DB: PubMed Journal: Health Place ISSN: 1353-8292 Impact factor: 4.078
Fig. 11851 Census addresses and building outlines and deaths from 1854 Cholera outbreak in Soho, Central London.
T test results for difference in mean of comparable variables in 1851 and 1854 for addresses with recorded cholera deaths.
| N | Mean of difference in count | Std. of mean | t | p | |
|---|---|---|---|---|---|
| Persons at address | 167 | 3.9 | 0.64 | 6.03 | 0.00 |
| Males at address | 47 | 5.1 | 4.39 | 7.98 | 0.00 |
| Females at address | 47 | 3.5 | 5.62 | 4.31 | 0.00 |
| Persons per room | 128 | −0.1 | 0.09 | −1.39 | 0.17 |
| Children (under 16 years) | 46 | 3.2 | 4.43 | 5.56 | 0.00 |
| M2 per person | 45 | −1.8 | 0.83 | −2.19 | 0.03 |
Note: Differences in the N values arises from variability in demographic data recorded in the 1854 visitation records.
Sources: 1851 Population Census; General Board of Health 1855.
Selected characteristics of population and households in Snow's study area in 1851 (percentages).
| Persons at address | 1 | 2–3 | 4–5 | 6–9 | 10–14 | 15–19 | 20 and over |
|---|---|---|---|---|---|---|---|
| Whole study area | 1.5 | 7.7 | 11.4 | 25.5 | 20.1 | 13.0 | 20.7 |
| Streets with at least one death | 1.1 | 5.5 | 9.2 | 23.1 | 19.5 | 14.8 | 26.7 |
| Streets without any deaths | 2.3 | 11.7 | 15.6 | 30.0 | 21.4 | 9.7 | 9.4 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 and over | |
| Whole study area | 47.8 | 13.4 | 8.3 | 8.1 | 6.5 | 5.7 | 9.9 |
| Streets with at least one death | 39.3 | 13.2 | 9.4 | 9.7 | 8.3 | 7.4 | 12.7 |
| Streets without any deaths | 64.4 | 13.7 | 6.2 | 5.0 | 3.1 | 2.6 | 4.9 |
| 1 | 2–3 | 4–5 | 6–9 | 10–14 | 15–19 | 20 and over | |
| Whole study area | 9.6 | 26.9 | 25.4 | 21.4 | 4.9 | 1.2 | 0.1 |
| Streets with at least one death | 9.3 | 38.3 | 26.2 | 20.1 | 4.2 | 1.2 | 0.6 |
| Streets without any deaths | 10.4 | 32.7 | 22.6 | 25.2 | 7.0 | 1.3 | 0.8 |
| 0–15 | 16–24 | 25–39 | 40–54 | 55–64 | 65 and over | ||
| Whole study area | 29.3 | 19.0 | 28.3 | 15.4 | 5.0 | 3.0 | |
| Streets with at least one death | 28.3 | 19.0 | 28.4 | 15.8 | 5.2 | 3.3 | |
| Streets without any deaths | 24.7 | 21.0 | 30.8 | 15.9 | 4.7 | 2.8 | |
| London or Middlesex | Other UK | Overseas | |||||
| Whole study area | 48.8 | 47.2 | 4.1 | ||||
| Streets with at least one death | 49.5 | 47.1 | 3.4 | ||||
| Streets without any deaths | 46.5 | 47.2 | 6.1 | ||||
| Solitary | Unrelated group | Married without children | Married with children | Generationally extended from head | Multiple groups | Institution | |
| Whole study area | 3.8 | 3.7 | 11.2 | 52.6 | 12.4 | 4.5 | 0.8 |
| Streets with at least one death | 3.8 | 3.3 | 11.4 | 53.3 | 6.4 | 4.3 | 0.8 |
| Streets without any deaths | 4.0 | 5.1 | 10.6 | 50.1 | 7.2 | 4.1 | 0.9 |
| Working in dress | Domestic | Conveying and transport | Food | Professional occupations | Working in metals | ||
| Whole study area | 29.0 | 20.8 | 7.0 | 6.8 | 5.0 | 4.8 | |
| Streets with at least one death | 7.0 | 18.7 | 1.9 | 5.4 | 4.1 | 2.3 | |
| Streets without any deaths | 6.2 | 26.1 | 2.9 | 3.3 | 7.5 | 1.8 |
Notes: For definitions of household unit type see Higgs et al., 2013. Figures for separate indicators exclude missing data. General and undefined occupations were excluded from analysis. Whole study area refers to the area covered by Snow's report (see Fig. 1).
Source: 1851 Population Census.
Fig. 2Spatial distribution of selected demographic and socio-economic indicators from 1851 Census across Snow's study area.
Fig. 3Kernel density estimation of cholera mortality using (N = 623).
Fig. 4Kernel density estimation of cholera mortality rate for addresses categorized in selected occupational types.
Source: 1851 Population Census.
Fig. 5Kernel density estimation of cholera mortality rate for addresses with the percentage of younger or older residents in the upper quartile or residential density, m2 per person and household in the lower quartile of the range.
Occupation prevalence at addresses where deaths from cholera occurred (percentages).
| HISCO occupation of head of household (HoH) | Address occupation determined by largest household | Address occupation determined by number of persons | Persons at address in specified occupation | 25–49% | 50–74% | 75–99% | 100% |
|---|---|---|---|---|---|---|---|
| of persons at address in occupation category | |||||||
| Persons working in agriculture | 0.6 | 0.6 | 0.4 | 0.0 | 50.0 | 0.0 | 50.0 |
| Persons working in building and construction | 4.9 | 4.3 | 3.6 | 50.0 | 21.4 | 7.1 | 7.1 |
| Persons working in commercial occupations | 2.2 | 1.8 | 1.6 | 33.3 | 16.7 | 0.0 | 50.0 |
| Persons working in conveying and transport | 6.2 | 6.5 | 5.9 | 23.8 | 38.1 | 0.0 | 38.1 |
| Persons working domestic service | 4.6 | 4.9 | 6.1 | 43.8 | 25.0 | 0.0 | 31.3 |
| Persons working in utilities | 0.3 | 0.3 | 0.3 | 100.0 | 0.0 | 0.0 | 0.0 |
| Persons working in government | 4.3 | 4.3 | 3.6 | 21.4 | 14.3 | 7.1 | 57.1 |
| Persons working professional occupations | 6.5 | 5.8 | 4.1 | 21.1 | 21.1 | 5.3 | 52.6 |
| Persons working defence | 0.6 | 0.6 | 0.5 | 0.0 | 50.0 | 0.0 | 50.0 |
| Persons working in wood and brick | 0.6 | 0.6 | 0.4 | 0.0 | 0.0 | 0.0 | 100.0 |
| Persons working chemicals | 0.6 | 0.6 | 0.6 | 0.0 | 0.0 | 0.0 | 100.0 |
| Persons working dress | 25.8 | 34.5 | 43.0 | 29.5 | 40.2 | 6.3 | 23.2 |
| Persons working in food | 14.5 | 12.9 | 10.2 | 16.7 | 23.8 | 2.4 | 57.1 |
| Persons working in metals | 7.7 | 5.8 | 5.5 | 31.6 | 36.8 | 0.0 | 31.6 |
| Persons working in paper | 1.5 | 1.2 | 1.1 | 25.0 | 0.0 | 25.0 | 50.0 |
| Persons working precious metals | 2.5 | 1.8 | 1.2 | 0.0 | 16.7 | 16.7 | 66.7 |
| Persons working in skins, hides, etc. | 0.9 | 0.9 | 0.6 | 33.3 | 0.0 | 0.0 | 66.7 |
| Persons working in textiles | 2.2 | 1.8 | 1.7 | 0.0 | 50.0 | 0.0 | 50.0 |
| Persons working in wood sector | 6.5 | 5.5 | 4.3 | 27.8 | 16.7 | 0.0 | 55.6 |
| Persons working in or around mines | 1.2 | 0.6 | 0.4 | 50.0 | 0.0 | 0.0 | 50.0 |
| Persons in general or undefined work | 4.3 | 3.1 | 3.2 | 20.0 | 20.0 | 20.0 | 40.0 |
| Persons with unspecified or no occupation | 1.5 | 1.2 | 1.7 | 0.0 | 0.0 | 25.0 | 50.0 |
| Total | 100 | 100 | 100 | ||||
Note: Addresses where no cholera deaths occurred and the Poland Street workhouse excluded from analysis. When presenting the percentage of persons at address in occupation category the lowest range (<25%) has not been included, which results in the four values presented not summing to 100%.
Source: 1851 Population Census.