Literature DB >> 32820481

New Insights into the Pathogenesis, Risk Factors, and Treatment of Portal Vein Thrombosis in Patients with Cirrhosis.

Oana Nicoară-Farcău1,2, Guillem Soy2,3,4, Marta Magaz2,3,4, Anna Baiges2,3,4, Fanny Turon2,3,4, Angeles Garcia-Criado4,5, Marta Barrufet4,5, Marta Burrel4,5, Virginia Hernández-Gea2,3,4, Juan Carlos García-Pagán2,3,4.   

Abstract

Portal vein thrombosis (PVT) is a frequent event in patients with cirrhosis regardless of etiology. Notwithstanding the commonality of the problem, the pathophysiology and risk factors for PVT in cirrhosis are largely unknown. The clinical impact of PVT in the natural history of cirrhosis is unclear, indications for PVT treatment are not well defined, and treatment recommendations are based on experts' opinion and consensus only. Therefore, this review aims to summarize current knowledge of mechanisms and risk factors for PVT development and assess the current evidence of PVT management, with a special focus on strategies of anticoagulation and transjugular intrahepatic portosystemic shunt placement. Thieme. All rights reserved.

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Year:  2020        PMID: 32820481     DOI: 10.1055/s-0040-1715473

Source DB:  PubMed          Journal:  Semin Thromb Hemost        ISSN: 0094-6176            Impact factor:   4.180


  6 in total

Review 1.  Direct oral anticoagulant administration in cirrhotic patients with portal vein thrombosis: What is the evidence?

Authors:  Marco Biolato; Mattia Paratore; Luca Di Gialleonardo; Giuseppe Marrone; Antonio Grieco
Journal:  World J Hepatol       Date:  2022-04-27

Review 2.  Evolution of Nonmalignant Portal Vein Thrombosis in Liver Cirrhosis: A Pictorial Review.

Authors:  Shixue Xu; Xiaozhong Guo; Benqiang Yang; Fernando Gomes Romeiro; Massimo Primignani; Nahum Méndez-Sánchez; Eric M Yoshida; Andrea Mancuso; Frank Tacke; Carlos Noronha Ferreira; Valerio De Stefano; Xingshun Qi
Journal:  Clin Transl Gastroenterol       Date:  2021-10-01       Impact factor: 4.488

Review 3.  The Pathophysiology of Portal Vein Thrombosis in Cirrhosis: Getting Deeper into Virchow's Triad.

Authors:  Aina Anton; Genís Campreciós; Valeria Pérez-Campuzano; Lara Orts; Joan Carles García-Pagán; Virginia Hernández-Gea
Journal:  J Clin Med       Date:  2022-02-02       Impact factor: 4.241

4.  Nonmalignant portal vein thrombi in patients with cirrhosis consist of intimal fibrosis with or without a fibrin-rich thrombus.

Authors:  Ellen G Driever; Fien A von Meijenfeldt; Jelle Adelmeijer; Robbert J de Haas; Marius C van den Heuvel; Chandrasekaran Nagasami; John W Weisel; Constantino Fondevila; Robert J Porte; Anabel Blasi; Nigel Heaton; Stephen Gregory; Pauline Kane; William Bernal; Yoh Zen; Ton Lisman
Journal:  Hepatology       Date:  2021-12-05       Impact factor: 17.298

5.  The portal vein in patients with cirrhosis is not an excessively inflammatory or hypercoagulable vascular bed, a prospective cohort study.

Authors:  Ellen G Driever; Marta Magaz; Jelle Adelmeijer; Fanny Turon; Anna Baiges; Pol Olivas; Valeria Pérez-Campuzano; Virginia Hernandez-Gea; Annabel Blasi; Juan-Carlos Garcia-Pagan; Ton Lisman
Journal:  J Thromb Haemost       Date:  2022-07-11       Impact factor: 16.036

Review 6.  [Portal vein thrombosis-treatment options].

Authors:  C Steib; M Guba; M Seidensticker
Journal:  Gastroenterologe       Date:  2021-02-11
  6 in total

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