Literature DB >> 3281924

Isolation and structure of a new ansamycin antibiotic kanglemycin A from a Nocardia.

N J Wang1, Y Fu, G H Yan, G H Bao, C F XU, C H He.   

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Year:  1988        PMID: 3281924     DOI: 10.7164/antibiotics.41.264

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


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  4 in total

1.  Synthesis and evaluation of dual-action kanglemycin-fluoroquinolone hybrid antibiotics.

Authors:  James Peek; Bimal Koirala; Sean F Brady
Journal:  Bioorg Med Chem Lett       Date:  2021-11-30       Impact factor: 2.823

2.  Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.

Authors:  James Peek; Mirjana Lilic; Daniel Montiel; Aleksandr Milshteyn; Ian Woodworth; John B Biggins; Melinda A Ternei; Paula Y Calle; Michael Danziger; Thulasi Warrier; Kohta Saito; Nathaniel Braffman; Allison Fay; Michael S Glickman; Seth A Darst; Elizabeth A Campbell; Sean F Brady
Journal:  Nat Commun       Date:  2018-10-08       Impact factor: 14.919

3.  Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis.

Authors:  Hamed Mosaei; Vadim Molodtsov; Bernhard Kepplinger; John Harbottle; Christopher William Moon; Rose Elizabeth Jeeves; Lucia Ceccaroni; Yeonoh Shin; Stephanie Morton-Laing; Emma Claire Louise Marrs; Corinne Wills; William Clegg; Yulia Yuzenkova; John David Perry; Joanna Bacon; Jeff Errington; Nicholas Edward Ellis Allenby; Michael John Hall; Katsuhiko S Murakami; Nikolay Zenkin
Journal:  Mol Cell       Date:  2018-09-20       Impact factor: 17.970

4.  A Semisynthetic Kanglemycin Shows In Vivo Efficacy against High-Burden Rifampicin Resistant Pathogens.

Authors:  James Peek; Jiayi Xu; Han Wang; Shraddha Suryavanshi; Matthew Zimmerman; Riccardo Russo; Steven Park; David S Perlin; Sean F Brady
Journal:  ACS Infect Dis       Date:  2020-08-25       Impact factor: 5.084

  4 in total

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