Literature DB >> 3281846

Thyroid cancer: the case for total thyroidectomy.

O H Clark1, K Levin, Q H Zeng, F S Greenspan, A Siperstein.   

Abstract

Since there are no prospective studies concerning the treatment of thyroid cancer, there continues to be a considerable disagreement about the 'best' or most appropriate form of surgical treatment for patients with papillary or follicular thyroid cancer. Some surgeons recommend selective treatment depending upon the type of thyroid tumor and stage of the disease. Some advocate thyroid lobectomy and isthmusectomy, some near total thyroidectomy, and some total thyroidectomy for patients with papillary and follicular thyroid cancer. Total thyroidectomy for thyroid cancer would be the treatment of choice for virtually all patients with thyroid cancers if it could be done without complications. We therefore reviewed 160 consecutive patients who had total thyroidectomy for suspected or proven thyroid cancer to determine the complication rate of total thyroidectomy. One hundred and three patients had primary operations, 57 had reoperations with completion of total thyroidectomy and 124 had thyroid cancer. Serious complications (i.e. vocal cord paralysis or hypoparathyroidism) included two cases of transient bilateral recurrent nerve palsy, two patients with presumed transient unilateral vocal cord paralysis, three recurrent laryngeal nerves that were purposely sacrificed because of invasion of the nerve, and one case of permanent hypoparathyroidism. Two other patients developed postoperative wound infections. Only one of the permanent complications, the case of permanent hypoparathyroidism, could have been avoided by a lesser procedure. The experienced surgeon can perform a total thyroidectomy with minimal morbidity, and this procedure has certain theoretical and practical advantages. It should not be done, however, if it will result in a significant complication rate and, in selected patients, it may be preferable to leave a small amount of thyroid tissue to protect the blood supply to the parathyroid glands or recurrent laryngeal nerve.

Entities:  

Mesh:

Year:  1988        PMID: 3281846     DOI: 10.1016/0277-5379(88)90273-8

Source DB:  PubMed          Journal:  Eur J Cancer Clin Oncol        ISSN: 0277-5379


  19 in total

1.  Bilaterality in papillary thyroid carcinoma: does it influence prognosis?

Authors:  Jason D Prescott; Sareh Parangi
Journal:  Ann Surg Oncol       Date:  2012-01       Impact factor: 5.344

Review 2.  Central lymph node dissection in differentiated thyroid cancer.

Authors:  Matthew L White; Paul G Gauger; Gerard M Doherty
Journal:  World J Surg       Date:  2007-05       Impact factor: 3.352

3.  Complications in thyroid surgery for carcinoma: one institution's surgical experience.

Authors:  Antonio Toniato; Isabella Merante Boschin; Andrea Piotto; Maria Rosa Pelizzo; Annamaria Guolo; Mirto Foletto; Eric Casalide
Journal:  World J Surg       Date:  2008-04       Impact factor: 3.352

4.  Completion thyroidectomy in differentiated thyroid cancer: When to perform?

Authors:  Abdullah Kısaoğlu; Bünyami Özoğul; Müfide Nuran Akçay; Gürkan Öztürk; Sabri Selçuk Atamanalp; Bülent Aydınlı; Salih Kara
Journal:  Ulus Cerrahi Derg       Date:  2014-03-01

5.  Prognostic factors and management in thyroid cancer--consensus or controversy?

Authors:  S K Grebe; I D Hay
Journal:  West J Med       Date:  1996-09

Review 6.  The role of surgery in the management of differentiated thyroid cancer.

Authors:  S K Grebe; I D Hay
Journal:  J Endocrinol Invest       Date:  1997-01       Impact factor: 4.256

7.  Completion thyroidectomy: effect of timing on clinical complications and oncologic outcome in patients with differentiated thyroid cancer.

Authors:  Gabriel Glockzin; Matthias Hornung; Klaus Kienle; Katrin Thelen; Marita Boin; Andreas G Schreyer; Hamid R Lighvani; Hans J Schlitt; Ayman Agha
Journal:  World J Surg       Date:  2012-05       Impact factor: 3.352

8.  Telomere length is related to alternative splice patterns of telomerase in thyroid tumors.

Authors:  Yongchun Wang; Alan K Meeker; Jeanne Kowalski; Hua-Ling Tsai; Helina Somervell; Christopher Heaphy; Lauren E Sangenario; Nijaguna Prasad; William H Westra; Martha A Zeiger; Christopher B Umbricht
Journal:  Am J Pathol       Date:  2011-07-16       Impact factor: 4.307

Review 9.  Thyroid cancer: a review of treatment and follow-up.

Authors:  L Vini; C Harmer; V R McCready
Journal:  Ann Nucl Med       Date:  1996-02       Impact factor: 2.668

10.  Recurrent thyroid cancer. Role of surgery versus radioactive iodine (I131)

Authors:  M Coburn; D Teates; H J Wanebo
Journal:  Ann Surg       Date:  1994-06       Impact factor: 12.969

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