Literature DB >> 32817488

Draining the FEN1s for cancer therapy.

Giacomo G Rossetti1, Sotirios K Sotiriou2, Thanos D Halazonetis3.   

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Year:  2020        PMID： 32817488      PMCID： PMC7486731          DOI： 10.1073/pnas.2014862117

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  15 in total

Review 1.  PARP family enzymes: regulation and catalysis of the poly(ADP-ribose) posttranslational modification.

Authors:  Marie-France Langelier; Travis Eisemann; Amanda A Riccio; John M Pascal
Journal:  Curr Opin Struct Biol       Date:  2018-11-24       Impact factor: 6.809

2.  Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

Authors:  Katharina Schlacher; Nicole Christ; Nicolas Siaud; Akinori Egashira; Hong Wu; Maria Jasin
Journal:  Cell       Date:  2011-05-13       Impact factor: 41.582

3.  The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors.

Authors:  L Nathan Tumey; David Bom; Bayard Huck; Elizabeth Gleason; Jianmin Wang; Daniel Silver; Kurt Brunden; Sherry Boozer; Stephen Rundlett; Bruce Sherf; Steven Murphy; Tom Dent; Christina Leventhal; Andrew Bailey; John Harrington; Youssef L Bennani
Journal:  Bioorg Med Chem Lett       Date:  2005-01-17       Impact factor: 2.823

Review 4.  PARP inhibitors: Synthetic lethality in the clinic.

Authors:  Christopher J Lord; Alan Ashworth
Journal:  Science       Date:  2017-03-16       Impact factor: 47.728

5.  RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination.

Authors:  B H Lok; A C Carley; B Tchang; S N Powell
Journal:  Oncogene       Date:  2012-09-10       Impact factor: 9.867

6.  Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.

Authors:  Helen E Bryant; Niklas Schultz; Huw D Thomas; Kayan M Parker; Dan Flower; Elena Lopez; Suzanne Kyle; Mark Meuth; Nicola J Curtin; Thomas Helleday
Journal:  Nature       Date:  2005-04-14       Impact factor: 69.504

7.  The Importance of Poly(ADP-Ribose) Polymerase as a Sensor of Unligated Okazaki Fragments during DNA Replication.

Authors:  Hana Hanzlikova; Ilona Kalasova; Annie A Demin; Lewis E Pennicott; Zuzana Cihlarova; Keith W Caldecott
Journal:  Mol Cell       Date:  2018-07-05       Impact factor: 17.970

8.  Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication.

Authors:  Katy Stokes; Alicja Winczura; Boyuan Song; Giacomo De Piccoli; Daniel B Grabarczyk
Journal:  Nucleic Acids Res       Date:  2020-06-25       Impact factor: 16.971

9.  Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

Authors:  Kristen E Mengwasser; Richard O Adeyemi; Yumei Leng; Mei Yuk Choi; Connor Clairmont; Alan D D'Andrea; Stephen J Elledge
Journal:  Mol Cell       Date:  2019-01-24       Impact factor: 19.328

10.  Visualization of recombination-mediated damage bypass by template switching.

Authors:  Michele Giannattasio; Katharina Zwicky; Cindy Follonier; Marco Foiani; Massimo Lopes; Dana Branzei
Journal:  Nat Struct Mol Biol       Date:  2014-09-07       Impact factor: 15.369
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  1 in total

Review 1.  Small-Molecule Inhibitors Targeting FEN1 for Cancer Therapy.

Authors:  Fan Yang; Zhigang Hu; Zhigang Guo
Journal:  Biomolecules       Date:  2022-07-20
  1 in total

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